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Can your immune system predict lung infection worsening?

NCT ID NCT07363798

Knowledge-focused Sponsor: Seoul National University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how the body's immune response and nutrition are linked to the progression of nontuberculous mycobacterial pulmonary disease (NTM-PD), a chronic lung infection. Researchers will analyze immune cells from the lungs and blood of 50 adults with confirmed or suspected NTM-PD. They will also assess nutritional status and body composition. The goal is to find better ways to predict which patients will need treatment as their disease worsens.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors identify which patients with NTM lung disease are at higher risk of worsening, allowing for earlier and more personalized monitoring.
What could go wrong
This is an observational study, not a treatment trial. It will not test any new drug or therapy. The results may not lead to immediate changes in patient care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants will be recruited from adults with confirmed or suspected nontuberculous mycobacterial pulmonary disease who are scheduled to undergo bronchoscopy as part of routine clinical evaluation or disease monitoring according to established NTM management guidelines. The study population consists of patients receiving standard-of-care clinical assessment and follow-up, without any additional procedures performed solely for research purposes.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older * Confirmed or suspected nontuberculous mycobacterial pulmonary disease * Active pulmonary tuberculosis excluded by standard microbiologic testing * Undergoing bronchoscopy as part of routine clinical evaluation or disease monitoring * Able and willing to provide written informed consent Exclusion Criteria: * Active pulmonary tuberculosis confirmed by microbiologic testing * Positive latent tuberculosis infection test * Current active malignancy requiring treatment * History of solid organ transplantation or hematopoietic stem cell transplantation * Use of systemic immunosuppressive medications * Diagnosis of autoimmune disease * Use of biologic agents or planned initiation of biologic therapy * Acute lower respiratory tract infection requiring treatment within 4 weeks prior to bronchoscopy * Pregnancy

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Conditions

The condition(s) this trial relates to.

Disease Progression pulmonary non-tuberculous mycobacterial infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Nontuberculous mycobacterial lung disease Nontuberculous mycobacterial pulmonary disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • SMG-SNU Boramae Medical Center

    Seoul, Dongjak-gu, 07061, South Korea

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