Can a Vacuum-Powered dressing speed up diabetic wound healing?
NCT ID NCT07745075
First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time
Summary
This study tests whether a vacuum-assisted wound dressing (negative pressure wound therapy) helps diabetic foot ulcers heal better than standard moist dressings. Sixty adults with chronic foot ulcers will be randomly assigned to one of the two treatments, and their wounds will be tracked for three months using a detailed wound assessment tool. The goal is to see if the vacuum approach leads to faster or more complete healing.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Negative pressure wound therapy (NPWT), also known as vacuum-assisted closure (VAC), which uses a sealed foam dressing and a vacuum to draw wound edges together and remove fluid.
- What this could lead to
- If effective, NPWT could become a preferred treatment for diabetic foot ulcers, potentially reducing healing time and lowering the risk of amputation.
- What could go wrong
- This is a small, single-center trial, so results may not apply broadly. NPWT requires specialized equipment and can be uncomfortable; there is also a risk of infection or skin irritation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
60 people
The number who actually took part.
- Started
-
Jan 2026
- Finished
-
May 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 80 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 18 years or older. * Diagnosed with superficial chronic diabetic foot ulcers (partial- or full-thickness) located on the plantar surface, metatarsal heads, or sole (Grade 1/clean ulcers). Had a wound length ranging from 10 to 15 cm. Had controlled diabetes mellitus with stable comorbid conditions (e.g., hypertension or non-end-stage renal disease). * Were able to speak and read Arabic. * Were able to perform activities of daily living (ADLs) independently. * Provided voluntary written informed consent to participate in the study Exclusion Criteria: * Underlying osteomyelitis, Charcot's joint/arthropathy, or DFUs classified as Wagner Grade 3, 4, or 5. * Severe peripheral vascular/arterial diseases, venous insufficiency, or bilateral involvement of both feet. * Coagulopathic conditions, active bleeding tendencies, or severe immunocompromising diseases. * Cognitive or mental impairments preventing informed participation. * Severe diabetic complications (e.g., acute cerebrovascular disease). * Pregnancy, active fever, or acutely infected wounds at baseline.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Diabetic foot ulcer healing trajectories are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
the National Center for Diabetes, Endocrinology, and Genetics (NCDEG)
Amman, Dours, 009627, Jordan