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Which drug best prevents blood pressure drops during spinal anesthesia in older adults?

NCT ID NCT07662408

Disease control Sponsor: Sohag University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests two medications, norepinephrine and phenylephrine, to see which one better prevents low blood pressure caused by spinal anesthesia in patients aged 60 and older undergoing hip surgery. Participants receive one of the two drugs right after the spinal block, and their heart rate and blood pressure are closely monitored. The goal is to find a safer, more effective way to maintain stable blood pressure during surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
norepinephrine and phenylephrine
What this could lead to
If one drug works better, it could become the preferred choice to prevent dangerous drops in blood pressure during spinal anesthesia in older adults.
What could go wrong
This is a small, early-phase trial with only 62 patients, so results may not apply to everyone. Both drugs can cause side effects like slow heart rate or high blood pressure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 62 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 100 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 60 years or older. 2. ASA physical status I-III. 3. Scheduled for elective hip surgery under subarachnoid block. 4. Willing to provide written informed consent. Exclusion Criteria: 1. Patient refusal. 2. Contraindications to subarachnoid block. 3. Severe cardiac disease. 4. Uncontrolled hypertension. 5. Allergy to study drugs. 6. Emergency surgery. 7. Monoamine oxidase inhibitor use. 8. Cognitive impairment preventing informed consent.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Orthopedic hip sugery in eldely patients Patients undergoing orthopedic hip surgery under spinal anesthesia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sohag university hospital

    RECRUITING

    Sohag, Egypt