Could Pre-Surgery radiation zap breast cancer before it spreads?
NCT ID NCT03909282
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 43 times
Summary
This study compares standard surgery alone versus a short course of radiotherapy followed by surgery for women with ductal carcinoma in situ (DCIS), a very early form of breast cancer. The goal is to see if pre-surgery radiation can completely eliminate the cancer cells in the removed tissue. Fifty women with small, non-palpable DCIS will be randomly assigned to one of the two groups, and researchers will check for any remaining cancer after surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Stanford University
RECRUITINGStanford, California, 94304, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
partial breast irradiation (radiotherapy)
What this could lead to
If successful, this approach could reduce the chance of DCIS returning after surgery and may allow less extensive surgery.
What could go wrong
This is a small, early-phase pilot study with only 50 participants, so results may not apply broadly. Radiotherapy also carries risks like skin irritation or damage to nearby tissues.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.