Could a non-opioid cocktail replace fentanyl for kidney stone pain?
NCT ID NCT07368738
First seen Feb 01, 2026 · Last updated May 25, 2026 · Updated 20 times
Summary
This study tests whether a combination of non-opioid pain relievers (acetaminophen and ketorolac) can control pain as well as or better than the standard opioid fentanyl during a procedure that breaks up kidney stones with shockwaves. About 266 adults will be randomly assigned to receive either the non-opioid or opioid regimen. Researchers will compare pain scores, procedure tolerability, and side effects like nausea or low blood pressure.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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St. Joseph's Hospital
Saint John, New Brunswick, E2L 3L6, Canada
Conditions
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