New air-bladder test aims to spot dangerous leg clots without needles
NCT ID NCT06519435
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new, non-invasive way to measure blood flow in the legs of people who may have deep vein thrombosis (a blood clot). Researchers will use an air-filled bladder under a compression cuff to see how well blood moves. The goal is to improve detection of clots without using needles or X-rays. About 500 adults who recently had a leg ultrasound will take part.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2024
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Subjects with venous ultrasound evaluation performed to rule out deep vein thrombosis
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Venous ultrasound study to evaluate for lower extremity DVT unilateral and/or bilateral within previous 72 hours. Exclusion Criteria: * Patients with inaccessible target limb (ultrasound limb) due to bandages (wound, burn, lesion, etc) or cast. * Patients with leg trauma, fracture, above or below knee amputation, or other condition in which compressing on the calf is medically inappropriate or not possible. * Patients unable to provide informed written consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Timing of blood thinners after childbirth bleeding may prevent clots without causing more harm
- New fingerstick test for blood thinner monitoring put to the test
- New Clot-Busting device could ease Long-Term leg pain