New ultrasound test may replace invasive heart exams for chest pain patients
NCT ID NCT07422818
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a non-invasive ultrasound of the heart can diagnose blood vessel problems in people with chest pain but no blocked arteries. About 35 patients who previously had an invasive heart test will get an ultrasound instead. The goal is to see if the ultrasound can spot the same issues without needing a catheter inside the body.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 35 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age between 18 and 90 years; 2. ICA performed within the previous 12 months from enrollment and characterized by: (a) absence of obstructive CAD (\<50% diameter reduction or FFR by \>0.80); (b) invasive assessment of epicardial/microvascular spasm by acetylcholine test; 3. Signed informed consent. Exclusion Criteria: 1. Presentation as an acute coronary syndrome (i.e. unstable chest pain) or a typical history of variant angina (frequent angina pain at rest with ST-segment elevation at the ECG, caused by recurrent coronary spasm); 2. Previous coronary revascularization with surgical intervention; 3. Asthma or known intolerance or contraindications to dipyridamole; 4. Serious medical conditions, including renal failure (eGFR \<30 mL/min), liver diseases, malignancies, and acute or chronic inflammatory diseases; 5. Pregnancy; 6. Psychological conditions that might hamper patient co-operation; 7. Any condition that, in the judgment of the investigators, would make difficult for the patient to complete the study protocol; 8. Missed informed consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
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How to take part
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
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