Brain zaps may sharpen memory – scientists test the idea
NCT ID NCT07468279
First seen Jun 26, 2026 · Last updated Aug 28, 2026 · Updated 3 times
Summary
This study tests whether mild electrical stimulation on the scalp can improve how the brain handles memory and self-control. Researchers will give healthy adults either real or fake stimulation while they perform tasks. The goal is to understand the link between brain waves and cognitive performance.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- transcranial alternating current stimulation (tACS) via Starstim device
- What this could lead to
- If successful, this could clarify how brain rhythms influence memory and attention, potentially guiding future therapies for cognitive decline.
- What could go wrong
- This is an early-stage, small study in healthy volunteers, not a treatment trial. Results may not apply to people with memory disorders, and the stimulation effects may be subtle or inconsistent.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Jan 2031
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 59 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18 years and older * Fluent in English * Normal or corrected-to-normal vision * Willing to be photographed Exclusion Criteria: * Must not have ever had an injury to the head that's caused you to be knocked out for a period of time (e.g., from a fall, blow to the head, road traffic accident). * Must not have an uncorrected vision or physical disability that interferes with your ability to see stimuli presented briefly on a computer screen or click a mouse button rapidly. * Must not have a history of epilepsy, convulsions, or seizures (except childhood febrile seizures). * Must not have a history of fainting or syncope. * For female participants, they must not be pregnant and/or must not think they might be pregnant. * Must not have skin problems like eczema, dermatitis, or open wounds on the scalp. * Must not have had prior brain surgery. * Must not have any metal located in the head/neck (except for dental work i.e., braces, permanent retainers, etc.) * Must not have any devices or other implants located in/near their head. This includes cochlear implants and aneurysm clips, cardiac pacemaker, or any other implanted electronic device. * Must not have a current (active) alcohol or substance use disorder, must have no recent history of withdrawal symptoms, and must be able to safely abstain from alcohol and non-prescribed/illicit drugs for at least 24 hours before the session. * Must not have any alcohol on the day of the session, must limit alcohol consumption to no more than 2 drinks (if legally permitted) in the prior 24 hours, and must not use any non-prescribed or illicit drugs in the 24 hours before the session. * Must not be sick with a fever, sleep-deprived, or feel dizzy, unwell, or intoxicated. * Must also have eaten and had fluids but not have consumed more caffeine than they typically consume. * Must not be taking anticonvulsant/anti-epileptic drugs or have ever taken them within their lifetime. * Must not be taking benzodiazepines or have taken them within the past 3 months. * Must not have had a recent change (start, stop, dose change) for any psychiatric/psychotropic medications within the past 3 months. * Must not be taking Bupropion (Wellbutrin, Zyban), Tricyclic antidepressants (e.g., amitriptyline, imipramine, clomipramine, etc.), Antipsychotics (clozapine; chlorpromazine, haloperidol, etc.), or Tramadol or have taken them within the past 3 months. * Must not have experienced cardiac problems, fibrillation, or have taken medications associated with cardiac conditions within the past 3 months. * Must not meet the diagnostic threshold for Autism Spectrum Disorder, Intellectual Disability, or Psychotic Disorders.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Florida International University
RECRUITINGMiami, Florida, 33199, United States
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