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Radiation boost may keep melanoma at bay for immunotherapy patients

NCT ID NCT04594187

First seen Feb 18, 2026 · Last updated Jun 16, 2026 · Updated 17 times

Summary

This study looks at whether giving radiation to the lymph nodes after surgery can lower the chance of melanoma returning in people who are already receiving immunotherapy. About 168 adults with high-risk melanoma that has spread to a sentinel lymph node will take part. The goal is to see if adding radiation reduces the risk of cancer coming back in the same area.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baptist - MD Anderson Cancer Center

    RECRUITING

    Jacksonville, Florida, 32207, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cooper Hospital UNIV MED CTR.

    RECRUITING

    Camden, New Jersey, 08103, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.