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Study explores why some patients respond better to physical therapy

NCT ID NCT04929171

Knowledge-focused Sponsor: University of Michigan Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This pilot study looked at 30 people with chronic neck or shoulder pain from myofascial pain syndrome. Researchers wanted to see if certain pain features (called nociplastic pain) affect how well patients respond to physical therapy. Participants were followed for 3 months after starting physical therapy. The goal is to better understand which patients benefit most from this treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help tailor physical therapy approaches based on pain type, improving treatment for people with myofascial pain.
What could go wrong
This is a small pilot study with only 30 participants, so results may not apply to everyone. It is observational, not testing a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

30 people

The number who actually took part.

Started

May 2016

Finished

Nov 2019

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants were drawn from new patients evaluated at a tertiary care spine and musculoskeletal clinic.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * English-speaking participants * Diagnosed by their physician with non-acute (more than two weeks) neck and/or shoulder girdle primary myofascial pain * Referred to a physical therapy treatment. Exclusion Criteria: * In an effort to reduce the potential that another medical condition could lead to a secondary myofascial pain response, extensive comorbid exclusion criterion. * Use of chronic high-dose opioid medication greater than 100 mg oral morphine equivalents per day. * Individuals receiving or applying for compensation or disability. * The inability to provide informed consent. * Severe physical impairment (e.g., blindness, deafness) * Co-morbid medical condition limiting function (e.g., malignant cancer) * Reported illicit drug use * Severe psychiatric condition that would limit judgment. * Lack of internet access.

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Conditions

The condition(s) this trial relates to.

myofascial pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Myofascial pain Physical therapy

Contacts and locations

Locations

  • University of Michigan

    Ann Arbor, Michigan, 48108, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.