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Reflex test may help predict pain procedure success

NCT ID NCT02774694

Diagnosis Sponsor: Benno Rehberg-Klug Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused This study
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study is testing whether measuring the nociceptive flexion reflex (a spinal reflex) can predict which patients with chronic back or neck pain will get significant pain relief from interventional procedures like epidural injections or nerve blocks. Researchers will measure the reflex threshold using a device called Paintracker and compare it to pain reduction at 1 week, 1 month, and 3 months. The study aims to improve patient selection for these common but variably effective treatments.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors identify which patients are most likely to get pain relief from injections or nerve blocks, making treatment more personalized.
What could go wrong
This is an observational study, not a treatment trial. The reflex test may not accurately predict outcomes, and the study is currently suspended, so results may be delayed or never completed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 350 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Included will be patients treated by the interventional pain management team of the department of anaesthesiology of the Geneva University Hospitals HUG

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients with chronic low back or neck pain (duration \>3 months) * scheduled for the following interventions: epidural injection, facet block, medial branch block, facet radiofrequency denervation, spinal cord stimulator implantation Exclusion Criteria: * inability to understand the patient information or the study questionnaires * patients \<18 years old * patients with implanted pacemakers or defibrillators

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome Low Back Pain Neck Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic pain Low back pain Neck pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hôpitaux Universitaires de Genève

    Geneva, 1205, Switzerland

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