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Shocking spasticity: new trial zaps arm stiffness with targeted pulses

NCT ID NCT07321158

Symptom relief Sponsor: University of West Attica Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a short burst of electrical stimulation to the arm muscles can reduce spasticity—stiffness and tightness—in people who have had a stroke or other brain or spinal cord injury. About 45 adults with upper limb spasticity will be randomly assigned to receive either high or low pulse duration electrical stimulation, or standard care alone. Researchers will measure changes in muscle activity, range of motion, and daily function to see which approach works best.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 45 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * diagnosis by neurologist with first damage of pyramidal tract with upper limb spasticity * absence of cognitive dysfunction * normal vital signs * absence of pharmacological treatment of spasticity (per os pharmacological treatment does not affect spasticity results and was not an exclusion criteria on patients' recruitment). Exclusion Criteria: * prior neurological damage to pyramidal tract * cognitive decline * dermatological damages * prior musculoskeletal dysfunction on the upper limb with spasticity * presence of metallic residues on the spastic upper limb * presence of seizures or psychiatric disorders * severe malformation or obesity (BMI \>30kg/m2) * history of coronary or other cardiovascular diseases (deep vein thrombosis, pulmonary embolism) * presence of systematic inflammatory disease * cancer on terminal stages * pregnancy.

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Conditions

The condition(s) this trial relates to.

Muscle Spasticity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pyramidal tract-related spasticity Upper motor neuron lesion

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Attikon Hospital

    RECRUITING

    Athens, Attica, 12462, Greece

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