Could a zap to the wrist ease stroke stiffness?

NCT ID NCT07617311

Symptom relief Sponsor: Izmir Katip Celebi University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a device that sends mild electrical pulses to wrist muscles can reduce spasticity (tightness) after a stroke. Four adults with post-stroke wrist stiffness will receive 20-minute sessions of neuromuscular electrical stimulation. Researchers will measure muscle reactions before and after to see if the treatment helps.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: Neuromuscular electrical stimulation (NMES) device
What this could lead to: If it works, this could point toward a simple, non-drug way to ease muscle tightness after a stroke.
What could go wrong: This is a very early, tiny study with only 4 people. It may not show clear benefits or apply to others. No long-term data.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 4 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 70 years * Post-stroke wrist flexor spasticity scored as Grade 2 or 3 on the Australian Spasticity Assessment Scale (ASAS), specifically selecting patients whose passive stretch resistance (post-catch response) can be easily overcome to ensure accurate and unconfounded electrophysiological evaluation. * Provision of voluntary, written informed consent prior to study enrollment. Exclusion Criteria: * Age \<18 or \>70 year * Contraindications to neuromuscular electrical stimulation (e.g., active electronic implants, history of epilepsy, or localized skin lesions preventing electrode placement) * Concomitant wrist contracture or pain sufficient to impede clinical evaluation * Structural abnormalities of the elbow joint obstructing median nerve stimulation * Median nerve neuropathy or injury in the ipsilateral upper extremity. * Non-stable dosage of antispastic medications within the 2 weeks prior to baseline * Initiation of medications affecting nerve conduction (e.g., antidepressants, anticonvulsants, anesthetics) within the past month; patients on a stable dose for \>1 month remain eligible * Botulinum toxin infiltration in the target spastic muscles within the preceding 3 months * History of neurolytic procedures targeting spasticity in the affected limb. * History of orthopedic or neurological surgery targeting spasticity in the affected limb * Cognitive impairment severe enough to compromise adherence to study protocols * Inability to maintain the required testing positions for the upper extremity joints (shoulder, elbow, forearm, and wrist) * Pregnancy

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post-stroke spasticity

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

1 site. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

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Could a zap to the wrist ease stroke stiffness?

What the study statuses mean