Zapping the good leg to heal the bad one: a new ACL rehab trick?
NCT ID NCT07156734
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether applying mild electrical stimulation to the healthy leg can improve muscle activation in the injured leg before and after ACL surgery. Researchers will measure muscle activity in 25 patients. The goal is to see if this simple technique could help overcome muscle weakness that often slows recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Neuromuscular Electrical Stimulation (NMES) device
- What this could lead to
- If it works, this could point toward a new rehab technique to improve muscle recovery after ACL injury.
- What could go wrong
- This is a very small, early study (25 people) with no treatment outcome—it only measures muscle activity. Results may not lead to any practical benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 25 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2025
An estimate. Start dates often move.
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients undergoing ACL surgery with semitendinosus tendon autograft in the Schulthess Clinic * Unilateral and primary ACL injury (with/without diagnoses of additional meniscus injury) Exclusion Criteria: * Previous surgery/ligament rupture in injured or uninjured knee or hip * Severe pain in the uninjured-side quadriceps or knee joint * Ongoing pregnancy * BMI \>30 kg/m² * Neuromuscular disease * Open wounds or tissue injuries on the anterior aspect of the thigh * Additional rupture of other knee ligaments (posterior cruciate ligament, medial collateral ligament, lateral collateral ligament) * Implanted metallic/electronic devices (cardiac pacemakers, defibrillators) * Patients getting a femoralis block (peripheral nerve block) after surgery will be excluded for the post-surgical appointment * Insufficient language comprehension
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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