Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could a zappy vest and protein drink save ICU Patients' muscles?

NCT ID NCT07430969

Disease control Sponsor: Wageningen University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study tests whether a single session of whole-body electrical muscle stimulation, with or without a dose of amino acids, can improve protein balance in sedated ICU patients on ventilators. Thirty adults will be split into three groups: sham stimulation, real stimulation, or real stimulation plus an amino acid drink. Researchers will measure muscle protein turnover and blood flow to see if these interventions help prevent muscle wasting.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
neuromuscular electrical stimulation and amino acid bolus
What this could lead to
If it works, this could point toward a simple, drug-free way to reduce muscle wasting in critically ill patients on ventilators.
What could go wrong
This is a very early, small study (30 people) looking at short-term protein balance, not long-term muscle strength or recovery. The results may not translate to real-world benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged ≥18 years * Expected to need mechanical ventilation for at least 48 hours, judged by physician * Expected to reach a Richmond Agitation-Sedation Scale (RASS) score of -4 or -5 (complete sedation), judged by physician * Informed consent obtained from the next-of-kin * Able to or are receiving gastric tube feeding * Have an arterial and a venous line in situ Exclusion Criteria: * Spinal cord injury * Previous surgery/local wounds that prohibit whole-body NMES * Conditions that prohibit NMES (such open wounds) * Chronic neuromuscular disorders (such as Amyotrophic lateral sclerosis (ALS)) * Acute Kidney Injury (AKI) II and III * Undergoing continuous veno-venous hemofiltration (CVVH) * Rhabdomyolysis * Neuromuscular blocking agents * In the caloric restriction period of refeeding syndrome * In prone position * Burn wounds * ICD/pacemaker * Pregnant * Deemed not suitable to participate based upon the judgement of the treating intensivist

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Muscle wasting in critically ill are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Muscle wasting in critically ill

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hospital Gelderse Vallei

    RECRUITING

    Ede, Netherlands

More trials for these conditions

Other studies related to the condition(s) this trial covers.