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Experimental cell combo for tough breast cancer halted after just 2 patients

NCT ID NCT05385705

First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 23 times

Summary

This early-phase study tested whether adding donor natural killer (NK) cells to standard antibody drugs (trastuzumab and pertuzumab) could help people with advanced HER2-positive breast cancer that had stopped responding to other treatments. Only 2 participants were enrolled before the study was terminated, so no conclusions about effectiveness can be drawn. The main goal was to check safety and tolerability.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hospital del Mar

    Barcelona, 08003, Spain

  • Vall d'Hebron Hospital

    Barcelona, 08035, Spain

Conditions

Explore the condition pages connected to this study.