Immunotherapy duo shows promise for Tough-to-Treat uterine cancer
NCT ID NCT05112601
First seen Jun 25, 2026 · Last updated Sep 18, 2026 · Updated 21 times
Summary
This phase II trial is testing whether combining two immunotherapy drugs, nivolumab and ipilimumab, works better than nivolumab alone for women with recurrent endometrial cancer that has a specific DNA repair defect (dMMR). About 81 participants will receive either the combination or single drug. The goal is to see if the combo can shrink tumors or slow cancer growth better than the single drug alone.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nivolumab and ipilimumab (immunotherapy drugs)
- What this could lead to
- If successful, this could provide a more effective treatment option for recurrent endometrial cancer with a specific genetic feature, potentially shrinking tumors and extending life.
- What could go wrong
- This is a phase II trial with only 81 participants, so results are preliminary. The combination may not be more effective than nivolumab alone and could cause additional side effects like immune-related inflammation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 81 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2022
- Expected to finish
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Jul 2032
An estimate. End dates often move.
- Lead sponsor
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A government research agency
The lead sponsor is the US National Institutes of Health.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with measurable or non-measurable (detectable) recurrent endometrial cancer * Measurable disease will be defined and monitored by RECIST v 1.1. Measurable disease is defined per RECIST 1.1 criteria as at least one lesion that can be accurately measured in at least one dimension (longest diameter to be recorded). Each lesion must be \>= 10 mm when measured by computed tomography (CT) or magnetic resonance imaging (MRI). Lymph nodes must be \>= 15 mm in short axis when measured by CT or MRI * Non-measurable (detectable) disease in a patient is defined in this protocol per RECIST 1.1 criteria as one who does not have measurable disease but has at least one of the following conditions: * All other lesions (or sites of disease), including small lesions (longest diameter \<10 mm or pathological lymph nodes with \>= 10 to \< 15 mm short axis), are considered non-measurable disease * Ascites and/or pleural effusion attributed to tumor * Solid and/or cystic abnormalities on radiographic imaging that do not meet RECIST 1.1 definitions for target lesions * Patients must have endometrial cancer with deficient mismatch repair system. All patients must have institutional immunohistochemistry (IHC) and/or microsatellite instability (MSI) testing to determine mismatch repair (MMR) status. MMR deficiency is defined as lack of expression of one or more mismatch repair proteins (MLH1, PMS2, MSH2, MSH6, EPCAM) by immunohistochemistry and/or presence of microsatellite instability high using the National Cancer Institute (NCI)-5plex and Promega v1.2 assays, or institutional standards (e.g. next-generation sequencing \[NGS\] panel) * Method(s) of detection of MMR deficiency will be recorded for each patient. An institutional pathology report, and additional reports if available, documenting these results must be submitted. Patients with "equivocal" results on MMR testing by immunohistochemistry may be eligible if they have documented evidence of microsatellite instability by MSI testing or by next generation sequencing assays. MMR testing by IHC may be used to resolve equivocal/indeterminate MSI results * Histologic confirmation of the original primary tumor is required (submission of pathology report(s) is required). Patients with the following histologic types are eligible: Endometrioid adenocarcinoma, mucinous adenocarcinoma, dedifferentiated/undifferentiated carcinoma, clear cell adenocarcinoma, mixed epithelial carcinoma, adenocarcinoma not otherwise specified (N.O.S.) * Patients may have received 1-2 prior lines of systemic therapy: * Prior anti-PD1/PD-L1 therapy is allowed if given in combination with chemotherapy or radiation therapy in adjuvant or primary metastatic/recurrent settings. Patients must have had a complete response and have disease progression/relapse with treatment-free interval of 12 months or more from last dose of therapy with immune check inhibition * Patients may have received prior radiation therapy for treatment of endometrial cancer. Prior radiation therapy may have included pelvic radiation therapy, extended field pelvic/para aortic radiation therapy, intravaginal brachytherapy, and/or palliative radiation therapy. All radiation therapy must be completed at least 4 weeks prior to registration * Patients may have received prior hormonal therapy for treatment of endometrial cancer. All hormonal therapy must be discontinued at least three weeks prior to registration * Any other prior therapy directed at the malignant tumor including chemotherapy, targeted agents, biologic agents, immunologic agents, and any investigational agents, must be discontinued at least 4 weeks prior to registration (6 weeks for nitrosoureas or mitomycin C) * Age \>= 18 * Eastern Cooperative Oncology Group (ECOG) Performance Status of 0, 1, or 2 * Platelets \>= 100,000/mcl * Absolute neutrophil count (ANC) \>= 1,500/mcl * Creatinine =\< 1.5 x institutional/laboratory upper limit of normal (ULN) * Total serum bilirubin level =\< 1.5 x ULN (patients with known Gilbert's disease who have bilirubin level =\<3 x ULN may be enrolled) * Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =\< 3 x ULN * Adequate oxygen saturation via pulse oximeter (CTCAE v.5.0 hypoxia \< grade 2 within 28 days prior to registration) * Thyroid-stimulating hormone (TSH) within normal limits (TSH \< ULN allowed in euthyroid patients on thyroid replacement therapy). TSH testing is only required if clinically indicated * Patients must have recovered from effects of recent surgery, radiotherapy or chemotherapy. At least 4 weeks must have elapsed since major surgery * As clinically indicated, patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, patients should be class 2B or better and have a corrected QT (QTc) interval \< 450 msec * The effects of nivolumab, and ipilimumab on the developing human fetus are unknown. For this reason and because nivolumab and ipilimumab are known to be teratogenic, women of child-bearing potential (WOCBP) must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry and for 5 months after the last dose of investigational drug. Women of childbearing potential must have a negative serum or urine pregnancy test (minimum sensitivity 25 IU/L or equivalent units of human chorionic gonadotropin \[HCG\]) within 24 hours prior to the start of nivolumab. Women must not be breastfeeding. Women who are not of childbearing potential (i.e., who are postmenopausal or surgically sterile) do not require contraception * WOCBP is defined as any female who has experienced menarche and who has not undergone surgical sterilization (hysterectomy or bilateral oophorectomy) or who is not postmenopausal. Menopause is defined clinically as 12 months of amenorrhea in a woman over 45 in the absence of other biological or physiological causes. In addition, women under the age of 55 must have a documented serum follicle stimulating hormone (FSH) level less than 40 mIU/mL * Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial * Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months of registration are eligible for this trial * Patients with evidence of chronic hepatitis B virus (HBV) infection must have an undetectable HBV viral load on suppressive therapy, if indicated * Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load * Patients with treated brain metastases are eligible if follow-up brain imaging after central nervous system (CNS)-directed therapy shows no evidence of progression and the patient is stable off steroids for at least one month * The patient or a legally authorized representative must provide study-specific informed consent prior to study entry and, for patients treated in the United States (U.S.), authorization permitting release of personal health information * Patients with vitiligo, endocrine deficiencies including thyroiditis managed with replacement hormones including physiologic corticosteroids are eligible * Patients with rheumatoid arthritis and other arthropathies, Sjogren's syndrome and psoriasis controlled with topical medication and patients with positive serology, such as antinuclear antibodies (ANA), anti-thyroid antibodies should be evaluated for the presence of target organ involvement and potential need for systemic treatment but should otherwise be eligible Exclusion Criteria: * Patients with a diagnosis of endometrial serous carcinoma or carcinosarcoma * Patients who received prior anti-PD1/PD-L1 therapy and had grade 3-4 or recurring grade 2 immune-related toxicities that led to dose delay or discontinuation of immunotherapy due to those toxicities * Patients who received anti-CTLA-4 therapy or other immunotherapeutic agents * Patients on chronic steroid therapy except those on replacement therapy at a daily dose of 10mg or less prednisone or equivalent * Patients on immunosuppressive therapy, with the exception of: * Intra-nasal, inhaled, topical or local steroid injections * Premedication for hypersensitivity reaction * Patients with active autoimmune disease or history of autoimmune disease that might recur, which may affect vital organ function or require immune suppressive treatment including systemic corticosteroids, should be excluded. These include but are not limited to patients with a history of immune related neurologic disease, multiple sclerosis, autoimmune (demyelinating) neuropathy, Guillain-Barre syndrome, myasthenia gravis; systemic autoimmune disease such as systemic lupus erythematosus (SLE), connective tissue diseases, scleroderma, inflammatory bowel disease (IBD), Crohn's, ulcerative colitis, hepatitis; and patients with a history of toxic epidermal necrolysis (TEN), Stevens-Johnson syndrome, or phospholipid syndrome should be excluded because of the risk of recurrence or exacerbation of disease * Patients with known immune impairment who may be unable to respond to anti-CTLA-4 antibody * Patients with uncontrolled intercurrent illness including, but not limited to: ongoing or active infection (except for uncomplicated urinary tract infection), interstitial lung disease or active, non-infectious pneumonitis, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements * Women who are pregnant or unwilling to discontinue nursing * Prior therapy with CTLA-4 inhibitors, or any other antibody or drug specifically targeting T-cell co-stimulation or immune checkpoint pathways * History of allergic reactions attributed to compounds of similar chemical or biologic composition to nivolumab, and/or ipilimumab including severe hypersensitivity reactions to any monoclonal antibody
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Get notified about this study
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
133 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Locations
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Abbott-Northwestern Hospital
RECRUITINGMinneapolis, Minnesota, 55407, United States
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Arnold Palmer Cancer Center Medical Oncology Norwin
RECRUITINGN. Huntingdon, Pennsylvania, 15642, United States
Contact Email: •••••@•••••
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Augusta University Medical Center
RECRUITINGAugusta, Georgia, 30912, United States
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Beacon Kalamazoo Cancer Center
SUSPENDEDKalamazoo, Michigan, 49009, United States
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Benefis Sletten Cancer Institute
RECRUITINGGreat Falls, Montana, 59405, United States
Contact Email: •••••@•••••
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Billings Clinic Cancer Center
RECRUITINGBillings, Montana, 59101, United States
Contact Email: •••••@•••••
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Bozeman Health Deaconess Hospital
RECRUITINGBozeman, Montana, 59715, United States
Contact Email: •••••@•••••
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Bronson Battle Creek
RECRUITINGBattle Creek, Michigan, 49017, United States
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Bronson Methodist Hospital
RECRUITINGKalamazoo, Michigan, 49007, United States
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Cancer and Hematology Centers of Western Michigan - Norton Shores
SUSPENDEDNorton Shores, Michigan, 49444, United States
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Carle BroMenn Medical Center
RECRUITINGNormal, Illinois, 61761, United States
Contact Email: •••••@•••••
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Carle Cancer Center
RECRUITINGUrbana, Illinois, 61801, United States
Contact Email: •••••@•••••
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Carle Cancer Institute Normal
RECRUITINGNormal, Illinois, 61761, United States
Contact Email: •••••@•••••
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Carle Physician Group-Effingham
RECRUITINGEffingham, Illinois, 62401, United States
Contact Email: •••••@•••••
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Carle Physician Group-Mattoon/Charleston
RECRUITINGMattoon, Illinois, 61938, United States
Contact Email: •••••@•••••
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Carle at The Riverfront
RECRUITINGDanville, Illinois, 61832, United States
Contact Email: •••••@•••••
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Case Western Reserve University
RECRUITINGCleveland, Ohio, 44106, United States
Contact Email: •••••@•••••
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Cleveland Clinic Cancer Center/Fairview Hospital
RECRUITINGCleveland, Ohio, 44111, United States
Contact Email: •••••@•••••
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Cleveland Clinic Foundation
RECRUITINGCleveland, Ohio, 44195, United States
Contact Email: •••••@•••••
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Community Hospital of Anaconda
RECRUITINGAnaconda, Montana, 59711, United States
Contact Email: •••••@•••••
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Community Medical Center
RECRUITINGMissoula, Montana, 59804, United States
Contact Email: •••••@•••••
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Corewell Health Grand Rapids Hospitals - Butterworth Hospital
RECRUITINGGrand Rapids, Michigan, 49503, United States
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Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
RECRUITINGSaint Joseph, Michigan, 49085, United States
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Corewell Health Lakeland Hospitals - Niles Hospital
RECRUITINGNiles, Michigan, 49120, United States
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Corewell Health Lakeland Hospitals - Saint Joseph Hospital
RECRUITINGSaint Joseph, Michigan, 49085, United States
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Corewell Health Reed City Hospital
RECRUITINGReed City, Michigan, 49677, United States
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Duke University Medical Center
RECRUITINGDurham, North Carolina, 27710, United States
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Duke Women's Cancer Care Raleigh
RECRUITINGRaleigh, North Carolina, 27607, United States
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Duluth Clinic Ashland
RECRUITINGAshland, Wisconsin, 54806, United States
Contact Email: •••••@•••••
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Essentia Health - Deer River Clinic
RECRUITINGDeer River, Minnesota, 56636, United States
Contact Email: •••••@•••••
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Essentia Health Cancer Center
RECRUITINGDuluth, Minnesota, 55805, United States
Contact Email: •••••@•••••
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Essentia Health Cancer Center-South University Clinic
RECRUITINGFargo, North Dakota, 58103, United States
Contact Email: •••••@•••••
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Essentia Health Hibbing Clinic
RECRUITINGHibbing, Minnesota, 55746, United States
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Essentia Health Sandstone
RECRUITINGSandstone, Minnesota, 55072, United States
Contact Email: •••••@•••••
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Essentia Health Virginia Clinic
RECRUITINGVirginia, Minnesota, 55792, United States
Contact Email: •••••@•••••
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Fairview Southdale Hospital
RECRUITINGEdina, Minnesota, 55435, United States
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Fred Hutchinson Cancer Center
ACTIVE_NOT_RECRUITINGSeattle, Washington, 98109, United States
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Geauga Hospital
RECRUITINGChardon, Ohio, 44024, United States
Contact Email: •••••@•••••
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Good Samaritan Hospital - Cincinnati
ACTIVE_NOT_RECRUITINGCincinnati, Ohio, 45220, United States
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Henrico Doctor's Hospital
RECRUITINGRichmond, Virginia, 23229, United States
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Hillcrest Hospital Cancer Center
RECRUITINGMayfield Heights, Ohio, 44124, United States
Contact Email: •••••@•••••
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IRMC Cancer Center
RECRUITINGIndiana, Pennsylvania, 15701, United States
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IU Health North Hospital
SUSPENDEDCarmel, Indiana, 46032, United States
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Indiana University/Melvin and Bren Simon Cancer Center
RECRUITINGIndianapolis, Indiana, 46202, United States
Contact Email: •••••@•••••
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Intermountain Health West End Clinic
RECRUITINGBillings, Montana, 59106, United States
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Kootenai Clinic Cancer Services - Post Falls
RECRUITINGPost Falls, Idaho, 83854, United States
Contact Email: •••••@•••••
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Kootenai Clinic Cancer Services - Sandpoint
RECRUITINGSandpoint, Idaho, 83864, United States
Contact Email: •••••@•••••
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Kootenai Health - Coeur d'Alene
RECRUITINGCoeur d'Alene, Idaho, 83814, United States
Contact Email: •••••@•••••
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Logan Health Medical Center
RECRUITINGKalispell, Montana, 59901, United States
Contact Email: •••••@•••••
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MU Health - University Hospital/Ellis Fischel Cancer Center
RECRUITINGColumbia, Missouri, 65212, United States
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MaineHealth Maine Medical Center- Scarborough
RECRUITINGScarborough, Maine, 04074, United States
Contact Email: •••••@•••••
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Mercy Hospital
RECRUITINGCoon Rapids, Minnesota, 55433, United States
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Miami Valley Hospital South
RECRUITINGCenterville, Ohio, 45459, United States
Contact Email: •••••@•••••
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Miller-Dwan Hospital
RECRUITINGDuluth, Minnesota, 55805, United States
Contact Email: •••••@•••••
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Minnesota Oncology - Edina
RECRUITINGEdina, Minnesota, 55435, United States
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Munson Medical Center
RECRUITINGTraverse City, Michigan, 49684, United States
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Nebraska Methodist Hospital
RECRUITINGOmaha, Nebraska, 68114, United States
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Northwest Cancer Center - Crown Point
RECRUITINGCrown Point, Indiana, 46307, United States
Contact Email: •••••@•••••
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Northwest Cancer Center - Hobart
RECRUITINGHobart, Indiana, 46342, United States
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Northwest Cancer Center - Valparaiso
RECRUITINGValparaiso, Indiana, 46383, United States
Contact Email: •••••@•••••
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Northwest Oncology LLC
RECRUITINGDyer, Indiana, 46311, United States
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Northwest Wisconsin Cancer Center
RECRUITINGAshland, Wisconsin, 54806, United States
Contact Email: •••••@•••••
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Ohio State University Comprehensive Cancer Center
RECRUITINGColumbus, Ohio, 43210, United States
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Oklahoma Cancer Specialists and Research Institute-Tulsa
ACTIVE_NOT_RECRUITINGTulsa, Oklahoma, 74146, United States
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Park Nicollet Clinic - Saint Louis Park
RECRUITINGSaint Louis Park, Minnesota, 55416, United States
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Parkland Memorial Hospital
RECRUITINGDallas, Texas, 75235, United States
Contact Email: •••••@•••••
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Providence Portland Medical Center
RECRUITINGPortland, Oregon, 97213, United States
Contact Email: •••••@•••••
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Providence Saint Vincent Medical Center
RECRUITINGPortland, Oregon, 97225, United States
Contact Email: •••••@•••••
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Regions Hospital
RECRUITINGSaint Paul, Minnesota, 55101, United States
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Roswell Park Cancer Institute
ACTIVE_NOT_RECRUITINGBuffalo, New York, 14263, United States
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Saint Alphonsus Cancer Care Center-Boise
SUSPENDEDBoise, Idaho, 83706, United States
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Saint Alphonsus Cancer Care Center-Caldwell
SUSPENDEDCaldwell, Idaho, 83605, United States
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Saint Alphonsus Cancer Care Center-Nampa
SUSPENDEDNampa, Idaho, 83687, United States
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Saint Alphonsus Cancer Care Center-Ontario
SUSPENDEDOntario, Oregon, 97914, United States
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Saint Catherine Hospital
RECRUITINGIndianapolis, Indiana, 46312, United States
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Saint Francis Regional Medical Center
RECRUITINGShakopee, Minnesota, 55379, United States
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Saint Luke's Cancer Institute - Boise
RECRUITINGBoise, Idaho, 83712, United States
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Saint Luke's Cancer Institute - Fruitland
RECRUITINGFruitland, Idaho, 83619, United States
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Saint Luke's Cancer Institute - Meridian
RECRUITINGMeridian, Idaho, 83642, United States
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Saint Luke's Cancer Institute - Nampa
RECRUITINGNampa, Idaho, 83687, United States
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Saint Mary Medical Center
RECRUITINGHobart, Indiana, 46342, United States
Contact Email: •••••@•••••
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Saint Vincent Frontier Cancer Center
RECRUITINGBillings, Montana, 59102, United States
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State University of New York Upstate Medical University
RECRUITINGSyracuse, New York, 13210, United States
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Swedish Cancer Institute-Edmonds
RECRUITINGEdmonds, Washington, 98026, United States
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Swedish Cancer Institute-Issaquah
RECRUITINGIssaquah, Washington, 98029, United States
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Swedish Medical Center-First Hill
RECRUITINGSeattle, Washington, 98122, United States
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The Community Hospital
RECRUITINGMunster, Indiana, 46321, United States
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The James Graham Brown Cancer Center at University of Louisville
RECRUITINGLouisville, Kentucky, 40202, United States
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Trinity Health Grand Rapids Hospital
SUSPENDEDGrand Rapids, Michigan, 49503, United States
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Trinity Health Muskegon Hospital
SUSPENDEDMuskegon, Michigan, 49444, United States
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UH Seidman Cancer Center at Lake Health Mentor Campus
RECRUITINGMentor, Ohio, 44060, United States
Contact Email: •••••@•••••
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UH Seidman Cancer Center at Saint John Medical Center
RECRUITINGWestlake, Ohio, 44145, United States
Contact Email: •••••@•••••
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UHHS-Chagrin Highlands Medical Center
RECRUITINGBeachwood, Ohio, 44122, United States
Contact Email: •••••@•••••
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UPMC Cancer Center at UPMC Horizon
RECRUITINGFarrell, Pennsylvania, 16121, United States
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UPMC Cancer Center at UPMC McKeesport
RECRUITINGMcKeesport, Pennsylvania, 15132, United States
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UPMC Cancer Center at UPMC Northwest
RECRUITINGSeneca, Pennsylvania, 16346, United States
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UPMC Cancer Center-Natrona Heights
RECRUITINGNatrona Heights, Pennsylvania, 15065, United States
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UPMC Cancer Center-Washington
RECRUITINGWashington, Pennsylvania, 15301, United States
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UPMC Cancer Centers - Arnold Palmer Pavilion
RECRUITINGGreensburg, Pennsylvania, 15601, United States
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UPMC Hillman Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
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UPMC Hillman Cancer Center - Monroeville
RECRUITINGMonroeville, Pennsylvania, 15146, United States
Contact Email: •••••@•••••
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UPMC Hillman Cancer Center - New Castle
RECRUITINGNew Castle, Pennsylvania, 16105, United States
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UPMC Hillman Cancer Center - Part of Frick Hospital
RECRUITINGMount Pleasant, Pennsylvania, 15666, United States
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UPMC Hillman Cancer Center - Passavant - Cranberry
RECRUITINGCranberry Township, Pennsylvania, 16066, United States
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UPMC Hillman Cancer Center Erie
RECRUITINGErie, Pennsylvania, 16505, United States
Contact Email: •••••@•••••
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UPMC Hillman Cancer Center at Butler Health System
RECRUITINGButler, Pennsylvania, 16001, United States
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UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
RECRUITINGMechanicsburg, Pennsylvania, 17050, United States
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UPMC Hillman Cancer Center in Coraopolis
RECRUITINGMoon Township, Pennsylvania, 15108, United States
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UPMC West Mifflin-Cancer Center Jefferson
RECRUITINGWest Mifflin, Pennsylvania, 15122, United States
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UPMC-Heritage Valley Health System Beaver
RECRUITINGBeaver, Pennsylvania, 15009, United States
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UPMC-Johnstown/John P. Murtha Regional Cancer Center
RECRUITINGJohnstown, Pennsylvania, 15901, United States
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UPMC-Magee Womens Hospital
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
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UPMC-Mercy Hospital
RECRUITINGPittsburgh, Pennsylvania, 15219, United States
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UPMC-Passavant Hospital
RECRUITINGPittsburgh, Pennsylvania, 15237, United States
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UPMC-Saint Clair Hospital Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15243, United States
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UPMC-Saint Margaret
RECRUITINGPittsburgh, Pennsylvania, 15215, United States
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UT Southwestern Clinical Center at Richardson/Plano
RECRUITINGRichardson, Texas, 75080, United States
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UT Southwestern/Simmons Cancer Center-Dallas
RECRUITINGDallas, Texas, 75390, United States
Contact Email: •••••@•••••
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UT Southwestern/Simmons Cancer Center-Fort Worth
RECRUITINGFort Worth, Texas, 76104, United States
Contact Email: •••••@•••••
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United Hospital
RECRUITINGSaint Paul, Minnesota, 55102, United States
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University Cancer and Blood Center LLC
SUSPENDEDAthens, Georgia, 30607, United States
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University Hospitals Parma Medical Center
RECRUITINGParma, Ohio, 44129, United States
Contact Email: •••••@•••••
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University of Alabama at Birmingham Cancer Center
RECRUITINGBirmingham, Alabama, 35233, United States
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University of Illinois
SUSPENDEDChicago, Illinois, 60612, United States
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University of Iowa/Holden Comprehensive Cancer Center
RECRUITINGIowa City, Iowa, 52242, United States
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University of Michigan Health - West
RECRUITINGWyoming, Michigan, 49519, United States
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University of New Mexico Cancer Center
RECRUITINGAlbuquerque, New Mexico, 87106, United States
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University of Oklahoma Health Sciences Center
RECRUITINGOklahoma City, Oklahoma, 73104, United States
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University of Rochester
RECRUITINGRochester, New York, 14642, United States
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University of Virginia Cancer Center
RECRUITINGCharlottesville, Virginia, 22908, United States
Contact Email: •••••@•••••
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UofL Health Medical Center Northeast
RECRUITINGLouisville, Kentucky, 40245, United States
Contact Email: •••••@•••••
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VCU Massey Comprehensive Cancer Center
ACTIVE_NOT_RECRUITINGRichmond, Virginia, 23298, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Email: •••••@•••••
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West Michigan Cancer Center
RECRUITINGKalamazoo, Michigan, 49007, United States
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Wilmot Cancer Institute at Webster
RECRUITINGWebster, New York, 14580, United States
Contact Email: •••••@•••••
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Women and Infants Hospital
RECRUITINGProvidence, Rhode Island, 02905, United States
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Women's Cancer Center of Nevada
RECRUITINGLas Vegas, Nevada, 89106, United States
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Women's Diagnostic Center - Munster
RECRUITINGMunster, Indiana, 46321, United States
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