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Immunotherapy duo takes on brain tumors in advanced melanoma

NCT ID NCT02374242

First seen Jan 05, 2026 · Last updated May 17, 2026 · Updated 18 times

Summary

This study tests whether the immunotherapy drugs nivolumab and ipilimumab, alone or together, can shrink melanoma tumors that have spread to the brain. It involves 76 adults with stage IV melanoma and at least one brain metastasis. The main goal is to see how many patients have their brain tumors shrink or disappear after 12 weeks of treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Melanoma Institute Australia

    Wollstonecraft, New South Wales, 2065, Australia

  • Peter MacCallum Cancer Centre

    East Melbourne, Victoria, 3002, Australia

  • Princess Alexandra Hospital

    Woolloongabba, Queensland, 4102, Australia

  • Royal Adelaide Hospital

    Adelaide, South Australia, 5000, Australia

Conditions

Explore the condition pages connected to this study.