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Immunotherapy duo shows promise against tough kidney cancer

NCT ID NCT03075423

First seen Oct 31, 2025 · Last updated May 24, 2026 · Updated 29 times

Summary

This study tested a combination of two immunotherapy drugs (nivolumab and ipilimumab) against standard treatments for people with a rare and advanced form of kidney cancer called non-clear cell renal cell carcinoma. The goal was to see if the combination could help patients live longer. About 316 participants who had not yet been treated for their advanced cancer took part in this phase 2 trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Centre François Baclesse

    Caen, France

  • Centre Hospitalier Départemental de Vendée

    La Roche-sur-Yon, France

  • Centre Hospitalier Universitaire de Bordeaux

    Bordeaux, France

  • Centre Leon Berard

    Lyon, France

  • Charite Berlin (Campus Virchow-Klinikum)

    Berlin, Germany

  • Gent University Hospital (Universitair Ziekenhuis Gent)

    Ghent, Belgium

  • Goethe University Frankfurt

    Frankfurt am Main, D-60590, Germany

  • Heine University

    Düsseldorf, Germany

  • Hospita de la Santa Creu i Sant Pau

    Barcelona, Spain

  • Hospital Clinic de Barcelona

    Barcelona, Spain

  • Hospital Univeritario 12 de Octubre

    Madrid, Spain

  • Hospital Vall d'Hebron

    Barcelona, Spain

  • Institut Gustave Roussy

    Paris, France

  • Klinik für Urologie, Universitätsklinik

    Jena, Germany

  • Klinikum Rechts der Isar der TU München

    München, Germany

  • Les Hoptaux Universitaires de Strasbourg

    Strasbourg, France

  • Medizinische Hochschule Hannover

    Hanover, Lower Saxony, 30625, Germany

  • Nationales Zentrum für Tumorerkrankungen (NCT)

    Heidelberg, 69120, Germany

  • Netherlands Cancer Institute

    Amsterdam, Netherlands

  • Royal Free London NHS Foundation Trust

    London, United Kingdom

  • The Christie NHS Foundation Trust

    Manchester, United Kingdom

  • Thomayer Hospital

    Prague, Czechia

  • University Hospital

    Homburg/Saar, Germany

  • University Hospital Erlangen

    Erlangen, 91054, Germany

  • University Hospital Greifswald

    Greifswald, Germany

  • University Hospital Hradec Králové

    Hradec Králové, Czechia

  • University Medical Center Groningen

    Groningen, Netherlands

  • University of Muenster

    Münster, 48149, Germany

  • Universitätsklinik Tübingen

    Tübingen, Germany

  • Universitätsklinikum Essen

    Essen, Germany

Conditions

Explore the condition pages connected to this study.