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New combo therapy shows promise for lung cancer that spread to the brain

NCT ID NCT05012254

First seen May 16, 2026 · Last updated May 23, 2026 · Updated 2 times

Summary

This study tests a combination of two immunotherapy drugs (nivolumab and ipilimumab) plus two rounds of chemotherapy as a first treatment for people with advanced lung cancer that has spread to the brain. The goal is to see if this approach can control the cancer in the brain for at least 6 months. The study involves 71 adults who have not had prior treatment for advanced disease and whose brain tumors are not causing symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hospital 12 De Octubre

    Madrid, Madrid, 28041, Spain

  • Hospital Clínico Universitario de Valladolid

    Valladolid, Valladolid, 47003, Spain

  • Hospital General Universitario de Valencia

    Valencia, Valencia, 46014, Spain

  • Hospital Provincial de Castellón

    Castellon, Castellon, 12002, Spain

  • Hospital Universitari Son Llatzer

    Palma de Mallorca, Palma de Mallorca, 07198, Spain

  • Hospital Universitari Vall d' Hebron

    Barcelona, Barcelona, 08035, Spain

  • Hospital Universitario Fundación Jiménez Díaz

    Madrid, Madrid, 28040, Spain

  • Hospital Universitario Insular de Gran canaria

    Las Palmas de Gran Canaria, Gran Canaria, 35016, Spain

  • Hospital Universitario La Fe

    Valencia, Valencia, 46026, Spain

  • Hospital Universitario Lucus Augusti

    Lugo, Lugo, 27003, Spain

  • Hospital Universitario Puerta de Hierro

    Majadahonda, Madrid, 28222, Spain

  • Hospital Universitario Regional de Málaga

    Málaga, Málaga, 29010, Spain

  • Hospital Universitario de Jaén

    Jaén, Jaén, 23007, Spain

  • Hospital Universitario de León

    León, León, 24071, Spain

  • Hospital de la Santa Creu i Sant Pau

    Barcelona, Barcelona, 08041, Spain

  • Hospitalario Universitario A Coruña

    A Coruña, La Coruña, 15006, Spain

  • ICO Badalona, Hospital Germans Trias i Pujol

    Badalona, Barcelona, 08916, Spain

  • ICO Hospitalet

    L'Hospitalet de Llobregat, Barcelona, 08908, Spain

Conditions

Explore the condition pages connected to this study.