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Triple-Drug attack shows promise for tough stomach cancer

NCT ID NCT04757363

First seen Mar 20, 2026 · Last updated Apr 29, 2026 · Updated 6 times

Summary

This study tests whether combining three drugs—nivolumab (an immunotherapy), FOLFOX (standard chemo), and regorafenib (a targeted therapy)—can safely control HER2-negative metastatic esophagogastric cancer. About 39 adults with advanced disease that has spread will receive this combination. The goal is to see if the mix keeps cancer from growing for at least 6 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Basking Ridge (All Protocol Activities)

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen (All Protocol Activities)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack (All Protocol Activities)

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth (All Protocol Activities)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (All Protocol Activities)

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Westchester (All Protocol Activities)

    Harrison, New York, 10604, United States

Conditions

Explore the condition pages connected to this study.