Beetroot and caffeine combo tested for cycling edge
NCT ID NCT07501806
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether taking nitrate (from beetroot juice) and caffeine together improves performance in a 3-minute all-out cycling test. Fifteen trained male cyclists completed four different supplement conditions in a randomized, double-blind trial. The goal was to see if the combination offers extra benefits over either supplement alone.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dietary nitrate (from beetroot juice) and caffeine
- What this could lead to
- If it works, this could point toward a simple dietary strategy to improve high-intensity cycling performance.
- What could go wrong
- This is a very small, early-stage study with only 15 participants, so results may not apply to all athletes. The effects may be small or not meaningful for real-world performance.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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15 people
The number who actually took part.
- Started
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Nov 2020
- Finished
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Nov 2021
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Male participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Males between the ages of 18 and 40 years of age * All participants must be trained cyclists, having participated in structured cycling training consisting of at least 2-3 sessions per week for at least 30-60 min each session during the past 12 months. * All participants must possess a relative max power output (Wmax) of 4.0 W/kg or greater OR a maximal oxygen consumption (VO2max) of 50 ml/kg/min. * All participants must be healthy and free of any disease as determined through the completion of a medical history questionnaire. * Body mass index (BMI) between 18.5 - 30 kg/m\^2 OR bodyfat percentage \<30% Exclusion Criteria: * All females * Males who are younger than 18 years and older than 40 years of age * Individuals who have a VO2max below 50 ml/kg/min and a relative Wmax below 4.0 W/kg * Individuals who fail to meet the minimum training requirements of 2-3 sessions per week of structured cycling training for at least 30-60 min per session during the past 12 months. * Any individual currently diagnosed with or being treated for any cardiovascular, renal, pulmonary, orthopedic, immunological, psychological or musculoskeletal disorder. * Any individual who is currently supplementing with a known or purported ergogenic aid (nitrates, caffeine, beta-alanine, bicarbonate, creative, Cordyceps) will be required to refrain from their use for 30 days before beginning the study. * Individuals who regularly smoke or have quit smoking within the last 6 months.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Exercise and Performance Nutrition Laboratory
Saint Charles, Missouri, 63301, United States
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