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Cancer drug combo tested in kids, but study stopped early

NCT ID NCT04544995

First seen Jan 21, 2026 · Last updated Apr 30, 2026 · Updated 14 times

Summary

This early-phase study aimed to find a safe dose of two drugs (niraparib and dostarlimab) given together to children and teens (ages 6 months to 18 years) with solid tumors that had come back or not responded to treatment. The goal was to see if the combination could shrink tumors or slow their growth. The study was terminated early, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • GSK Investigational Site

    Birmingham, B4 6NH, United Kingdom

  • GSK Investigational Site

    Sutton, SM2 5PT, United Kingdom

Conditions

Explore the condition pages connected to this study.