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New drug aims to slow Alzheimer's by targeting toxic brain tangles

NCT ID NCT06372821

First seen Jan 28, 2026 · Last updated May 25, 2026 · Updated 17 times

Summary

This early-stage study tests whether a drug called NIO752 can reduce the brain's production of tau, a protein that forms harmful tangles in Alzheimer's disease. Ten adults with mild to moderate Alzheimer's will receive either the drug or a placebo via spinal injection. The main goal is to measure tau production using a special labeling technique, not to treat symptoms directly.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University College London Hospitals NHS Foundation Trust

    RECRUITING

    London, NW1 2PG, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Washington University in St. Louis

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.