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Can black seed capsules tame borderline high blood pressure in women?

NCT ID NCT07494279

First seen Mar 27, 2026 · Last updated Jun 22, 2026 · Updated 16 times

Summary

This study tests whether a daily black seed extract supplement (Nisatol®) can help lower blood pressure in women with borderline high readings or a specific nighttime blood pressure pattern. 106 women will take either the supplement or a placebo for 12 weeks. Researchers will measure changes in blood pressure and heart rate to see if the supplement offers a natural way to manage early hypertension.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Rome Tor Vergata

    Roma, Italy

    Contact Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Nigella sativa (black seed) extract, standardized as Nisatol®

What this could lead to

If it works, this could point toward a natural supplement option for managing borderline high blood pressure in women without needing prescription drugs.

What could go wrong

This is a small, early-stage trial with only 106 women, so results may not apply to everyone. Supplements can have variable effects and may not lower blood pressure enough to be clinically meaningful.

Conditions

The condition(s) this trial relates to.

hypertensive disorder Prehypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.