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Could a daily supplement slow glaucoma damage?

NCT ID NCT05695027

First seen Nov 12, 2025 · Last updated May 20, 2026 · Updated 26 times

Summary

This study tests whether taking nicotinamide and pyruvate (N&P) supplements can help preserve vision in people with open-angle glaucoma. About 250 adults aged 35–85 will take either N&P or a placebo for 20 months, while continuing their standard glaucoma eye drops. The goal is to see if the supplements slow damage to the optic nerve and visual field.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Columbia University Irving Medical Center - 622 W 168th St

    New York, New York, 10032, United States

  • ColumbiaDoctors Ophthalmology - 880 Third Avenue

    New York, New York, 10022, United States

  • Stanford University Department of Ophthalmology

    Palo Alto, California, 94303, United States

Conditions

Explore the condition pages connected to this study.