Glaucoma patients may get vision boost from common supplements

NCT ID NCT05695027

First seen Nov 12, 2025 · Last updated May 14, 2026 · Updated 25 times

Summary

This study tests whether taking nicotinamide and pyruvate (N&P) supplements can help maintain eye health in people with open-angle glaucoma. About 250 adults aged 35-85 will take N&P or a placebo for 20 months, while continuing their standard glaucoma medications. The goal is to see if the supplements slow damage to the optic nerve and preserve vision.

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Contacts and locations

Locations

  • Columbia University Irving Medical Center - 622 W 168th St

    New York, New York, 10032, United States

  • ColumbiaDoctors Ophthalmology - 880 Third Avenue

    New York, New York, 10022, United States

  • Stanford University Department of Ophthalmology

    Palo Alto, California, 94303, United States

Conditions

Explore the condition pages connected to this study.