Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New hope for ulcerative colitis: experimental drug OD-07656 enters Mid-Stage trial

NCT ID NCT06850727

Disease control Sponsor: Odyssey Therapeutics Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called OD-07656 in people with moderate to severe ulcerative colitis, a chronic bowel disease. The goal is to see if it safely reduces symptoms like bleeding and diarrhea, and if it can make a follow-up treatment (vedolizumab) work better. About 57 adults will participate in this early-phase trial.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 57 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2025

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: The main inclusion criteria include but are not limited to the following: * Has a confirmed diagnosis of ulcerative colitis (UC) * Has moderate to severely active UC as defined by the 3-component Modified Mayo clinic score * Has an inadequate response, loss of response, or intolerance/medical contraindication to at least one of the following therapies: oral aminosalicylates, corticosteroids, immunosuppressants, anti-tumor necrosis factor biologic, anti-interleukin 12/23 biologic, Janus kinase inhibitors, or sphingosine-1-phosphate (S1P) modulators Exclusion Criteria: The main exclusion criteria include but are not limited to the following: * Has diagnosis of Crohn's disease or indeterminate colitis * Has had extensive colonic resection * Has colostomy or ileostomy * Has uncontrolled primary sclerosing cholangitis

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Uc - ulcerative colitis are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

inflammatory bowel disease ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Uc - ulcerative colitis Ulcerative colitis (UC)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    32 sites in 10 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Alfred Health

    RECRUITING

    Melbourne, 3004, Australia

  • CHUM

    RECRUITING

    Montreal, H2X OA9, Canada

  • CHUM - Pavillon R

    RECRUITING

    Polička, 1549, Czechia

  • Centrum Medyczne

    RECRUITING

    Bydgoszcz, Poland

  • Centrum Medyczne LukaMed

    RECRUITING

    Chojnice, Poland

  • Centrum Medyczne Medyk

    RECRUITING

    Rzeszów, Poland

  • Coastal Digestive Health

    RECRUITING

    Maroochydore, Australia

  • Danylo Halytsky Lviv National Medical University

    RECRUITING

    Lviv, 79000, Ukraine

  • Eastern Health

    RECRUITING

    Box Hill, Australia

  • Endoskopia Sp. z.o.o

    RECRUITING

    Sopot, Poland

  • Fiona Stanley Hospital

    RECRUITING

    Murdoch, 6150, Australia

  • IMSP Spitalul Clinic Republican Timofei Moneaga

    RECRUITING

    Chisinau, Md-2025, Moldova

  • Irbid Specialty Hospital

    RECRUITING

    Irbid, 21110, Jordan

  • Jordan University Hospital

    RECRUITING

    Amman, 11942, Jordan

  • Lviv Regional Clinical Hospital

    RECRUITING

    Lviv, 79010, Ukraine

  • Medical Network Company

    RECRUITING

    Warsaw, Poland

  • Medical University of Graz

    RECRUITING

    Graz, Austria

  • Medical centre of ARENSIA Exploratory Medicine LCC

    RECRUITING

    Kyiv, 01135, Ukraine

  • Montreal General Hospital/McGill University

    RECRUITING

    Montreal, Canada

  • Nowe zdrowie-CK, Kiełtucki

    RECRUITING

    Staszów, Poland

  • PCRN Auckland

    RECRUITING

    Auckland, 0622, New Zealand

  • PCRN Christchurch

    RECRUITING

    Christchurch, 0622, New Zealand

  • PCRN Tasman

    RECRUITING

    Nelson, 7011, New Zealand

  • PCRN Waikato

    RECRUITING

    Hamilton, 3200, New Zealand

  • PCRN Wellington

    RECRUITING

    Upper Hutt, 5018, New Zealand

  • Penta Hospitals Przychodnie

    RECRUITING

    Wroclaw, 54-239, Poland

  • Regional Clinical Hospital

    RECRUITING

    Ivano-Frankivsk, 76008, Ukraine

  • Royal Melbourne Hospital

    RECRUITING

    Parkville, Australia

  • Sunshine Coast University

    RECRUITING

    Birtinya, Australia

  • The Hospital of Lithuanian University of Health Sciences

    RECRUITING

    Kaunas, Lithuania

  • The Specialty Hospital (TSH) / Advanced Clinical Center

    RECRUITING

    Amman, Jordan

  • Vita Longa Sp. z.o.o.

    RECRUITING

    Katowice, Poland

More trials for these conditions

Other studies related to the condition(s) this trial covers.