New MRI scan could reveal hidden brain tumors
NCT ID NCT07272616
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new MRI sequence that aims to make brain tumors (metastases) more visible after a standard contrast injection. Researchers will compare the new method to the usual MRI in 100 adults with known or suspected brain tumors. The goal is to see if the new scan finds more or smaller tumors without increasing contrast dose or scan time.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Gadolinium-based contrast agent
- What this could lead to
- If successful, this new MRI method could help doctors find more brain tumors, especially small ones, leading to earlier and more accurate diagnosis.
- What could go wrong
- This is a small, early-phase study with only 100 participants. The new method may not detect more tumors than standard MRI, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients referred for clinical brain MRI with contrast at a university hospital radiology department in Sweden. Participants will be adults with known or suspected brain metastases undergoing routine post-gadolinium imaging as part of their diagnostic work-up.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older * Scheduled for clinical brain MRI with gadolinium contrast * Known or suspected brain metastases * Able to provide informed consent * Able to lie still for the duration of the MRI examination Exclusion Criteria: * Contraindications to MRI * Known allergy or contraindication to gadolinium-based contrast agents * Renal impairment (eGFR \< 30 mL/min/1.73m²) * Pregnant or breastfeeding * Inability to comply with study procedures
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Karolinska University Hospital
RECRUITINGStockholm, Solna, 1171 76, Sweden
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can doctors watch brain metastases instead of zapping them?
- Starving brain tumors of blood before surgery
- Tiny gadolinium particles aim to make brain radiation hit harder
- Brain scan may replace biopsy for tumor grading
- Can the choice of anesthesia shield the aging brain after tumor surgery?
- A sharper MRI could reveal radiation sensitivity of brain tumors