Breakthrough treatment could unlock transplants for the Hardest-to-Match patients
NCT ID NCT05345717
Summary
This small pilot study tested whether a combination of two drugs (belatacept and a proteasome inhibitor) could safely help patients who are 'highly sensitized'—meaning their immune systems are primed to reject most donor kidneys—find a compatible donor. The goal was to lower their antibody levels so they could receive a successful transplant. Five patients with end-stage kidney disease participated in this early-phase safety and effectiveness study.
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Contacts and locations
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Locations
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University of Chicago
Chicago, Illinois, 60637, United States
Conditions
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