New light imaging could replace the pinch test for scleroderma
NCT ID NCT05672992
First seen Nov 01, 2025 · Last updated Jun 21, 2026 · Updated 34 times
Summary
This study tests a new imaging method called spatial frequency domain imaging (SFDI) that uses near-infrared light to measure skin thickness in people with scleroderma. Researchers will compare SFDI to current methods like the pinch test, skin biopsy, and ultrasound in 78 participants over 3 years. If it works well, SFDI could become a fast, non-invasive tool to monitor disease activity.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Shapiro Outpatient Rheumatology Clinic at Boston Medical Center
Boston, Massachusetts, 02118, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could provide a quick, painless way to track skin fibrosis in scleroderma, replacing imprecise pinch tests.
What could go wrong
This is an early observational study, not a treatment trial. The new imaging method may not prove more accurate or practical than existing tools.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.