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New scan could spare elderly from unnecessary steroid side effects

NCT ID NCT07010484

Diagnosis Sponsor: Kresten Krarup Keller Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to improve how doctors diagnose polymyalgia rheumatica (PMR), a painful inflammatory condition common in older adults. Current methods often lead to misdiagnosis and unnecessary treatment with steroids, which have serious side effects. Researchers will use a new PET/MRI imaging technique in 149 adults over 50 to see if it can more accurately identify PMR and guide safer treatment decisions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 149 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Aug 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients suspected of and diagnosed with polymyalgia rheumatica are included.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients suspected of PMR seen at the Department of Rheumatology/internal medicine in Aarhus, Silkeborg, Horsens, Gødstrup, Randers, and Svendborg. 2. Age above 50. 3. Proximal extremity pain. Exclusion Criteria: 1. Oral, intravenous, intra-articular or intramuscular glucocorticoids within the last 2 months. 2. Previous prednisolone treatment for GCA/PMR. 3. Unable to give consent. 4. Proximal extremity pain duration for more than one year. 5. Symptoms of GCA (headache, scalp tenderness, jaw or tongue claudication, vision disturbances attributable to GCA, limb claudication). 6. Active malignant cancers within the last 5 years (except basal cell carcinoma). 7. Other known inflammatory rheumatic diseases (e.g. rheumatoid arthritis, polymyositis, spondyloarthritis, psoriatic arthritis, gout). 8. Uncontrolled diseases (e.g. severe active asthma, cardiac disease with NYHA class IV) 9. For MRI: Implants contraindicating MRI and BMI\>150 kg.

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Conditions

The condition(s) this trial relates to.

disease polymyalgia rheumatica

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Polymyalgia rheumatica (PMR)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    7 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Aarhus University Hospital

    RECRUITING

    Aarhus, Denmark

  • Central Jutland Regional Hospital

    RECRUITING

    Silkeborg, Denmark

  • Gødstrup Hospital

    NOT_YET_RECRUITING

    Gødstrup, Denmark

  • Horsens Regional Hospital

    NOT_YET_RECRUITING

    Horsens, Denmark

  • Odense University Hospital

    NOT_YET_RECRUITING

    Odense, Denmark

  • Randers Regional Hospital

    NOT_YET_RECRUITING

    Randers, Denmark

  • Svendborg Hospital

    NOT_YET_RECRUITING

    Svendborg, Denmark

More trials for these conditions

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