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New dental filling material put to the test in 5-Year study

NCT ID NCT06238999

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a new flowable composite filling material (TM Flow) for treating non-carious cervical lesions—damage to the tooth near the gum line not caused by cavities. 66 adults each receive two fillings (one experimental, one standard) in different teeth. Researchers will check for pain, sensitivity, and how well the fillings hold up over 5 years.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
TM Flow flowable composite dental filling material
What this could lead to
If successful, this could provide a safe and effective new option for treating non-carious cervical lesions, potentially improving dental restoration durability and aesthetics.
What could go wrong
This is a small, early-stage study (66 participants) comparing a new material to an existing one. Results may not apply to all patients or lesion types, and long-term performance is still unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

66 people

The number who actually took part.

Started

Feb 2024

Expected to finish

Dec 2029

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Informed Consent signed by the subject * Age: 18-65 years * 2 NCCL needing treatment, comparable in extend and size, preferably located in different quadrants * Vital teeth, regular sensitivity * Sufficient language skills * No active periodontitis * Preoperative VAS values \< 3 regarding tooth sensitivity on biting. Tooth sensitivity on temperature or touching (tooth brushing, probing) originating in the area of the NCCL is accepted. * Subject wishes to have a restoration as part of the study (written declaration of consent after detailed explanation) Exclusion Criteria: * Not completed hygiene phase or poor oral hygiene * Sufficient isolation of the cavity not possible * Patients with a proven allergy to one of the ingredients (methacrylates) * Patients with severe systemic diseases * Periodontally insufficient dentition * Pregnancy * Part of the development project team of TM Flow * Staff of the study management team * Staff of the internal clinic

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ivoclar Vivadent AG

    Schaan, Liechtenstein, 9494, Liechtenstein