New hope for Hard-to-Treat leukemia: triple drug combo shows promise
NCT ID NCT03862157
First seen Jan 12, 2026 · Last updated Jun 10, 2026 · Updated 26 times
Summary
This study tests a new combination of three drugs (azacitidine, venetoclax, and pevonedistat) in adults with a difficult-to-treat form of acute myeloid leukemia (AML). The goal is to find the best dose and see how well the drugs work together to control the cancer. About 40 participants will receive the treatment to measure safety and effectiveness.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.