New hope for Hard-to-Treat leukemia: triple drug combo shows promise

NCT ID NCT03862157

First seen Jan 12, 2026 · Last updated Jun 10, 2026 · Updated 26 times

Summary

This study tests a new combination of three drugs (azacitidine, venetoclax, and pevonedistat) in adults with a difficult-to-treat form of acute myeloid leukemia (AML). The goal is to find the best dose and see how well the drugs work together to control the cancer. About 40 participants will receive the treatment to measure safety and effectiveness.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.