New cholesterol fighter shows promise against current meds

NCT ID NCT06450366

Completed Disease control Sponsor: Merck Sharp & Dohme LLC Source: ClinicalTrials.gov ↗

Summary

This completed Phase 3 study tested whether a new drug called MK-0616 works better than existing cholesterol medications at lowering 'bad' LDL cholesterol. The trial involved 301 adults with high cholesterol who were already taking statin medications. Researchers compared MK-0616 against ezetimibe, bempedoic acid, or a combination of both over 8 weeks to see which was most effective.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Assuta Beersheba MC ( Site 0704)

Beersheba, 8489507, Israel
Barts Health NHS Trust-William Harvey Clinical Research Centre ( Site 0901)

London, England, EC1M 6BQ, United Kingdom
CIPREC-CIPREC Sede Arenales ( Site 1000)

Buenos Aires, Buenos Aires F.D., C1061AAS, Argentina
Cambridge Cardiac Care Centre ( Site 1603)

Cambridge, Ontario, N1R 6V6, Canada
Chang Gung Medical Foundation-Linkou Branch ( Site 0404)

Taoyuan District, 33305, Taiwan
Clinical Trials Research ( Site 1509)

Lincoln, California, 95648, United States
Diex Recherche Trois-Rivieres ( Site 1602)

Trois-Rivières, Quebec, G9A 4P3, Canada
EAP Sardenya ( Site 0800)

Barcelona, 08025, Spain
Fundacion Estudios Clinicos ( Site 1001)

Rosario, Santa Fe Province, S2000DEJ, Argentina
Healthcare Research Network - Chicago ( Site 1507)

Flossmoor, Illinois, 60422, United States
Hospices Civils de Lyon - Hopital Louis Pradel ( Site 0501)

Bron, Rhone, 69677, France
Hospital San Rafael de Coruna ( Site 0805)

A Coruña, La Coruna, 15006, Spain
Hospital Universitari Vall d'Hebron ( Site 0803)

Barcelona, 08035, Spain
Hospital Universitario Virgen de la Victoria-UGC Endocrinologia y nutricion ( Site 0801)

Málaga, Andalusia, 29010, Spain
Hospital de Figueres ( Site 0804)

Figueres, Gerona, 17600, Spain
Hôpital Arnaud de Villeneuve - CHU Montpellier ( Site 0505)

Montpellier, Herault, 34090, France
Hôpital Bichat - Claude-Bernard ( Site 0504)

Paris, 75018, France
Hôpital Nord Guillaume-et-René-Laennec / CHU de Nantes-CIC Endocrinology-Diabetology-Nutrition ( Sit

Nantes, Loire-Atlantique, 44093, France
Institut de Cardiologie de Montreal ( Site 1604)

Montreal, Quebec, H1T 1C8, Canada
Instituto de Investigaciones Clínicas Mar del Plata ( Site 1002)

Mar del Plata, Buenos Aires, B7600FZO, Argentina
L-MARC Research Center ( Site 1501)

Louisville, Kentucky, 40213, United States
Meir Medical Center. ( Site 0703)

Kfar Saba, 4428164, Israel
National Cheng Kung University Hospital-Internal Medicine ( Site 0403)

Tainan, 704, Taiwan
National Institute for Health Research UCLH Clinical Research Facility ( Site 0908)

London, London, City of, NW1 2PG, United Kingdom
National Taiwan University Hospital ( Site 0400)

Taipei, 10002, Taiwan
North York Diagnostic and Cardiac Centre ( Site 1605)

North York, Ontario, M6B 3H7, Canada
Piedmont Research Partners ( Site 1506)

Fort Mill, South Carolina, 29707, United States
Rainier Clinical Research Center ( Site 1502)

Renton, Washington, 98057, United States
Rambam Health Care Campus ( Site 0700)

Haifa, 3109601, Israel
Royal Free Hospital ( Site 0900)

London, England, NW3 2QG, United Kingdom
Taipei Veterans General Hospital-Department of Medicine ( Site 0402)

Taipei, 11217, Taiwan
The Medical Arts Health Research Group ( Site 1606)

Vancouver, British Columbia, V7M 2H4, Canada
Velocity Clinical Research Rockville ( Site 1503)

Rockville, Maryland, 20854, United States
Velocity Clinical Research, Gulfport ( Site 1505)

Gulfport, Mississippi, 39503, United States
Yitzhak Shamir Medical Center. ( Site 0702)

Beer Yaakov, 70300, Israel

Conditions

Explore the condition pages connected to this study.

HYPERCHOLESTEROLEMIA