First human trial tests promising new cancer drug combination

NCT ID NCT04777994

Recruiting now Disease control Sponsor: Calico Life Sciences LLC Source: ClinicalTrials.gov ↗

Summary

This early-stage study is testing a new drug called ABBV-CLS-484 in people with advanced solid tumors that have spread or returned after previous treatments. Researchers want to find safe doses when the drug is given alone and when combined with two other cancer medications. The trial will enroll 248 participants with specific cancers including head and neck, lung, and kidney cancers to see how their bodies handle the drug and if it shows any effectiveness against their tumors.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Beth Israel Deaconess Medical Center /ID# 252009
RECRUITING

Boston, Massachusetts, 02215-5400, United States
Carolina BioOncology Institute /ID# 225704
COMPLETED

Huntersville, North Carolina, 28078, United States
Centre Antoine-Lacassagne /ID# 252606
RECRUITING

Nice, Provence-Alpes-Côte d'Azur Region, 06189, France
Dana-Farber Cancer Institute /ID# 249642
RECRUITING

Boston, Massachusetts, 02215, United States
Duke Cancer Center /ID# 251975
RECRUITING

Durham, North Carolina, 27710, United States

Contact Phone: •••-•••-••••
Hadassah Medical Center /ID# 252366
RECRUITING

Jerusalem, Jerusalem, 91120, Israel
Hopital Foch /ID# 252607
RECRUITING

Suresnes, 92151, France
Hospital Universitario 12 de Octubre /ID# 257374
RECRUITING

Madrid, Madrid, 28041, Spain
Hospital Universitario HM Sanchinarro /ID# 228034
RECRUITING

Madrid, Madrid, 28050, Spain
IUCT Oncopole /ID# 252673
RECRUITING

Toulouse, Occitanie, 31059, France
Institut Català d'Oncologia (ICO) - L'Hospitalet /ID# 252524
RECRUITING

L'Hospitalet de Llobregat, Barcelona, 08907, Spain
Institut Paoli-Calmettes /ID# 260956
RECRUITING

Marseille, Bouches-du-Rhone, 13009, France
Johns Hopkins Hospital /ID# 254056
RECRUITING

Baltimore, Maryland, 21287, United States

Contact Phone: •••-•••-••••
Lifespan Cancer Institute at Rhode Island Hospital /ID# 225705
RECRUITING

Providence, Rhode Island, 02903-4923, United States
NEXT Oncology /ID# 225708
COMPLETED

San Antonio, Texas, 78229, United States
NYU Laura and Isaac Perlmutter Cancer Center - 34th Street /ID# 257869
RECRUITING

New York, New York, 10016, United States

Contact Phone: •••-•••-••••
National Cancer Center Hospital /ID# 225884
RECRUITING

Chuo-ku, Tokyo, 104-0045, Japan
Perelman Center for Advanced Medicine /ID# 250188
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

Contact Phone: •••-•••-••••
Rabin Medical Center /ID# 263631
RECRUITING

Petah Tikva, Central District, 4941492, Israel
Samsung Medical Center /ID# 260664
RECRUITING

Seoul, Seoul Teugbyeolsi, 06351, South Korea
Seoul National University Hospital /ID# 254635
RECRUITING

Seoul, Seoul Teugbyeolsi, 03080, South Korea
The Chaim Sheba Medical Center /ID# 226756
RECRUITING

Ramat Gan, Tel Aviv, 5265601, Israel
UPMC Hillman Cancer Ctr /ID# 225706
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
University of Arizona Cancer Center - Tucson /ID# 262698
RECRUITING

Tucson, Arizona, 85724, United States
University of Michigan Comprehensive Cancer Center Michigan Medicine /ID# 252010
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Texas MD Anderson Cancer Center /ID# 252004
RECRUITING

Houston, Texas, 77030, United States

Contact Phone: •••-•••-••••
University of Texas Southwestern Medical Center /ID# 251974
RECRUITING

Dallas, Texas, 75390-7208, United States
Wakayama Medical University Hospital /ID# 252988
RECRUITING

Wakayama, Wakayama, 641-8510, Japan
Yale University School of Medicine /ID# 225707
RECRUITING

New Haven, Connecticut, 06510, United States
Yonsei University Health System Severance Hospital /ID# 260665
RECRUITING

Seoul, 03722, South Korea

Conditions

Explore the condition pages connected to this study.

ADVANCED SOLID TUMOR CANCER