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Blood tests could track rare immune disease APDS

NCT ID NCT06694363

First seen Mar 25, 2026 · Last updated Jun 20, 2026 · Updated 10 times

Summary

This study aims to find new biomarkers in blood, urine, and stool to better screen and monitor Activated PI3K Delta Syndrome (APDS), a rare immune disorder. Researchers will collect samples from 14 patients over two years, including those starting a PI3K inhibitor treatment. The goal is to identify markers that reflect disease severity and treatment response, using advanced lab techniques.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU IUCT Oncopole - TOULOUSE

    NOT_YET_RECRUITING

    Toulouse, France

    Contact Email: •••••@•••••

  • Hôpital Haut Levêque - BORDEAUX

    NOT_YET_RECRUITING

    Bordeaux, 33000, France

    Contact Email: •••••@•••••

  • Hôpital Jeanne de Flandres - LILLE

    RECRUITING

    Lille, 59000, France

    Contact Email: •••••@•••••

  • Hôpital La Timone adulte - MARSEILLE

    NOT_YET_RECRUITING

    Marseille, 13000, France

    Contact Email: •••••@•••••

  • Hôpital Necker Enfants Malades - PARIS

    RECRUITING

    Paris, 75015, France

    Contact Email: •••••@•••••

  • Hôpital Pellerin Enfants - BORDEAUX

    NOT_YET_RECRUITING

    Bordeaux, 33000, France

    Contact Email: •••••@•••••

  • Hôpital des enfants - TOULOUSE

    NOT_YET_RECRUITING

    Toulouse, France

    Contact Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to better ways to monitor APDS disease activity and response to treatment using simple blood tests.

What could go wrong

This is a very small, early-stage study (14 participants) focused on finding biomarkers, not testing a treatment. The results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

activated PI3K-delta syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.