Massive data collection launched for brain surgery patients

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

* INCLUSION CRITERIA: 1. Participants must be age 4 and older. 2. Participants must seek care from, or be referred to the Surgical Neurology Branch for evaluation and management of neurosurgical conditions (such as central nervous system tumors, peripheral nerve tumors, epilepsy, Parkinson s disease, movement disorders, Chiari syndrome, central nervous system malformations, and pain disorders) 3. For adults: able to provide informed consent or having a legally-authorized representative to provide consent, if incapacitated 4. For minors: a parent or legal guardian who is able to provide consent. For immediate blood relatives of subjects having genetic testing only: 5. Blood relative of a subject who is suspected to have a genetic mechanism underlying their neurological disorder (for genetic testing only). EXCLUSION CRITERIA: 1\. Patients who are unable to undergo evaluation and treatment for a neurosurgical disorder 3.c. Participant Inclusion Criteria for the cohort with processing of biological samples only (for those subjects who are only having skin biopsies and/or saliva samples) 1. Participants must be age 4 and older. 2. Participants must seek care from or be referred to the Surgical Neurology Branch for evaluation and management of neurosurgical conditions (such as central nervous system tumors, peripheral nerve tumors, epilepsy, Parkinson s disease, movement disorders, Chiari syndrome, central nervous system malformations, and pain disorders) 3. For adults: able to provide informed consent or having a legally-authorized representative to provide consent, if incapacitated 4. For minors: a parent or legal guardian who is able to provide consent. 5. Be willing to consent for collection of clinical data or biological samples or their cryopreservation 3.D. Participant Exclusion Criteria for the cohort with processing of biological samples only (for those subjects who are only having skin biopsies and/or saliva samples) 1. Patients who are unable to undergo evaluation and treatment for a neurosurgical disorder 2. At the time of enrollment, subjects without an established diagnosis of a wellcharacterized disease entity with validated treatment algorithms. In such cases, proposed resource investment, in the opinion of the investigators, would not contribute to further advancement of knowledge