GPS for the brain: could neuronavigation boost stroke rehab?
NCT ID NCT07284017
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether using a brain-mapping system (neuronavigation) to guide magnetic stimulation (rTMS) helps stroke patients with arm weakness recover better than standard positioning. Thirty adults who had a stroke 2 weeks to 6 months ago will receive 10 sessions over 2 weeks. Researchers will measure arm function and treatment accuracy.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- repetitive transcranial magnetic stimulation (rTMS) guided by neuronavigation
- What this could lead to
- If it works, this could point toward a more precise and effective way to help stroke survivors regain arm movement.
- What could go wrong
- This is a small, early-stage trial with only 30 people. The improvement may be small or no better than standard rTMS. Results may not apply to all stroke patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * First-ever ischemic or hemorrhagic stroke confirmed by imaging. * Stroke causing unilateral upper limb weakness (MRC grade \<=3) * Stroke onset must be between 2 weeks and 6 months prior to enrollment (subacute phase). * Age between 20 and 85 years old. * Stable vital signs, clear consciousness, and no cognitive impairment. * Able to cooperate with assessments and treatment. * Written informed consent must be signed by the patient or a legal guardian. Exclusion Criteria: * Contraindications to TMS (e.g., metallic implants in head, pacemaker, cochlear implant). * History of epilepsy or seizures. * Pregnancy. * Severe cognitive or communication disorders, or inability to give informed consent. * Unstable medical conditions affecting participation. * Use of certain medications, including benzodiazepines, antidepressants, muscle relaxants (baclofen, tizanidine), or ongoing botulinum toxin injections for post-stroke spasticity. * Modified Rankin Scale (mRS) score \>=5 .
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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