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Zapping away Depression's dark thoughts: brain stimulation targets Mind-Wandering

NCT ID NCT04832685

First seen May 06, 2026 · Last updated May 24, 2026 · Updated 3 times

Summary

This study tests whether a non-invasive brain stimulation technique called LIFUP can reduce negative thinking and mind-wandering in people with depression. Researchers will use brain scans to see if calming a specific brain region (the posterior cingulate cortex) helps people with depression have fewer negative thoughts and feel more mindful. The study involves 80 adults with depression who will receive both real and sham stimulation to compare effects.

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.