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Large study to count hidden dangers of nerve blocks

NCT ID NCT07238933

Knowledge-focused Sponsor: Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 11, 2026 · Updated 1 time

Summary

This observational study will follow about 3,400 adults receiving single-shot regional anesthesia (nerve blocks) for surgery. Researchers aim to measure how often complications like nerve injury, bleeding, or lung puncture occur. The study does not test any new drug or treatment—it simply collects real-world data to better understand risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 3,396 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients (≥18 years) undergoing single-shot locoregional anesthesia of the upper limb, lower limb, or fascial blocks.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years. * Scheduled to undergo a single-shot nerve or fascial plane block. * Ability to provide written informed consent. Exclusion Criteria: * Performance of more than one single-shot nerve or fascial plane block within the same anatomical region or sensory distribution during the same procedure. * Use of continuous nerve or fascial plane catheter-based anesthesia. * Presence of a language barrier that, in the investigator's judgment, would prevent adequate follow-up.

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Conditions

The condition(s) this trial relates to.

pneumothorax

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Regional anesthesia Regional anesthesia block

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • ASST Papa Giovanni XXIII

    NOT_YET_RECRUITING

    Bergamo, Bergamo, 24127, Italy

  • Azienda Ospedale-Università Padova

    RECRUITING

    Padova, Padova, 35128, Italy

  • Irccs Humanitas Research Hospital

    NOT_YET_RECRUITING

    Rozzano, Milan, 20089, Italy

  • Spedali Civili di Brescia

    NOT_YET_RECRUITING

    Brescia, Brescia, 25123, Italy

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