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Simple blood test may predict rare nerve disease before symptoms start

NCT ID NCT06360289

First seen Nov 17, 2025 · Last updated May 18, 2026 · Updated 20 times

Summary

This study looks at a protein called NfL in the blood of people who carry a gene linked to a rare disease that damages nerves (hATTR amyloidosis). Researchers want to see if NfL levels can help detect when the disease starts, how it progresses, and how well treatments work. About 500 people with or without symptoms will give blood samples over time. This is an observational study, meaning no new treatment is tested.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Hospitalier Universitaire (CHU) Le Kremlin-Bicêtre Assistance Publique-Hôpitaux de Paris (APHP)

    RECRUITING

    Paris, Île-de-France Region, 94270, France

Conditions

Explore the condition pages connected to this study.