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Sciatica sufferers: which therapy eases pain better?

NCT ID NCT07050108

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two physical therapy techniques—neurodynamic mobilization and Mulligan SNAGs—for people with chronic sciatica caused by a disc problem. 66 participants completed the trial at Cairo University. Researchers measured pain intensity, pressure pain threshold, and leg movement range to see which approach worked better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
physical therapy techniques (neurodynamic mobilization and Mulligan SNAGs)
What this could lead to
If one technique proves better, it could offer a more effective non-surgical option for managing chronic sciatica pain.
What could go wrong
This is a small, completed trial with no phase designation, so results may not apply to all patients. Both techniques are generally low-risk, but individual responses vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

66 people

The number who actually took part.

Started

Aug 2025

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All the patients diagnosed as lumbar radiculopathy (L5-S1) for at least six months. Diagnosis was confirmed by physical, neurological examination (motor assessment, sensory assessment, reflexes) and radiological assessment (CT or MRI). * All patients has second grade of disc bulge which will detect from T2 axial view of MRI according to Fardon and Milette * All patients has unilateral radiculopathy and pain in the distribution of scaitic nerve. * The age of the patients will range from 35 to 50years . Their body mass index will range between( 22-25) Exclusion Criteria: * Bilateral and multilevel disc prolapse or bilateral radtadiating pain * acute pain (pain less than three months). * Presence of active infection in lumbar spine. * Any other spinal deformities. * Postoperative cases. * Cauda equine lesion. * Neoplasmic. * Spinal stenosis. * Mechanical low back pain. * Failed back syndrome.

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Conditions

The condition(s) this trial relates to.

sciatica

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Discogenic pain Sciatica

Contacts and locations

Locations

  • Faculty of physical therapy, Cairo University

    Cairo, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.