Scientists hunt for clues in neuroblastoma cells
NCT ID NCT01587300
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study collects tissue, blood, and bone marrow samples from 1,000 children with high-risk neuroblastoma. Researchers will analyze these samples to learn more about how the cancer grows and how to detect it better. The goal is to improve future treatments and monitoring of the disease.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could lead to better ways to detect neuroblastoma and track how well treatments are working.
- What could go wrong
- This is an observational biology study, not a treatment trial. It may not directly lead to new therapies, and results may take years to apply.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,000 people
The number the study aims to enrol. It can still change while the study runs.
- Start date
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Jul 2011
- Expected to finish
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Dec 2099
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Neuroblastoma patients from various NANT sites.
- Ages
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31 days to 99 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients must be greater than or 31 days of age. * Patients must have had a diagnosis of high risk neuroblastoma either by histological verification of neuroblastoma and/or demonstration of tumor cells in the bone marrow with increased urinary catecholamines. * All patients with refractory or recurrent high risk neuroblastoma at NANT institutions are eligible regardless of disease status (including no measurable or evaluable tumor) as long as they undergo a disease evaluation and appropriate samples are submitted. * Additionally, all patients with high risk neuroblastoma without relapse treated at a NANT institution are eligible if undergoing a disease evaluation, as long as Children's Oncology Group specimens are prioritized. Exclusion Criteria: * There are no exclusion criteria on this study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
15 sites in 2 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus
RECRUITINGAtlanta, Georgia, 30322, United States
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C.S Mott Children's Hospital
RECRUITINGAnn Arbor, Michigan, 48109, United States
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Children Hospital of Colorado
RECRUITINGAurora, Colorado, 80045, United States
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Children's Hospital Boston
RECRUITINGBoston, Massachusetts, 02115, United States
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Children's Hospital Los Angeles
RECRUITINGLos Angeles, California, 90027-0700, United States
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Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104-4318, United States
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Cincinnati Children's Hospital Medical Center
RECRUITINGCincinnati, Ohio, 45229-3039, United States
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Cook Children's Medical Center - Fort Worth
RECRUITINGFort Worth, Texas, 76104, United States
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Hospital for Sick Children
RECRUITINGToronto, Ontario, M5G 1X8, Canada
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Lucille Salter Packer Children's Hospital, Stanford University
COMPLETEDPalo Alto, California, 94305, United States
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Nationwide Children's Hospital
RECRUITINGColumbus, Ohio, 43205, United States
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Seattle Children's Hospital
RECRUITINGSeattle, Washington, 98105, United States
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St. Jude Children's Research Hospital
NOT_YET_RECRUITINGMemphis, Tennessee, 38105, United States
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UCSF Helen Diller Family Comprehensive Cancer Center
RECRUITINGSan Francisco, California, 94115, United States
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University of Chicago, Comer Children's Hospital
RECRUITINGChicago, Illinois, 60637, United States
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University of North Carolina
COMPLETEDChapel Hill, North Carolina, 27599, United States
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University of Texas Southwestern
NOT_YET_RECRUITINGDallas, Texas, 75235, United States
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Other studies related to the condition(s) this trial covers.
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- A simple blood test may reveal hidden infertility risk in young cancer survivors
- Can a shorter chemo combo tame High-Risk neuroblastoma?
- Can a radioactive 'Smart Bomb' take down resistant childhood cancers?