Brain scans may forecast language success in children with cochlear implants
NCT ID NCT05962359
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study investigates whether brain imaging can predict how well children with cochlear implants will develop language skills. Researchers are building models to forecast long-term language outcomes in English- and Spanish-speaking children. They are also testing a parent-led communication training program to see if it can help children predicted to have poorer language outcomes. The goal is to personalize therapy based on each child's predicted needs.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Parent-Implemented Communication Treatment (PICT)
- What this could lead to
- If successful, this could allow doctors to predict which children will struggle with language after cochlear implants and offer them targeted therapy early.
- What could go wrong
- The predictive models are still being developed and may not be accurate for all children. The behavioral therapy requires significant parent commitment and may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 700 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2023
- Expected to finish
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Jan 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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0 months to 5 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria (Arm 1): 1. Children with sensorineural hearing loss who meet clinical criteria for cochlear implantation in both ears who meet the following age criteria at time cochlear implant evaluation begins: * Age 5 years and under. * English or Spanish as the dominant language. 2. English or Spanish dominant language in the home. Inclusion Criteria (Arm 2): 1. Children with bilateral sensorineural hearing loss who meet clinical criterial for cochlear implantation 2. English dominant spoken language by family 3. Age at implantation of 36 months and younger when treatment begins 4. Parent or caregiver that is willing to participate who understands spoken English 5. Child is exposed to spoken language by at least one parent (total communication or auditory/oral) in the home Exclusion Criteria (Arm 1): 1. Severe motor and /or cognitive disability that would preclude evaluation of progress 2. Limited electrode insertion likely to significantly impact development of speech perception 3. Hearing loss due to bacterial meningitis 4. Neither English or Spanish as the dominant family language in the home Exclusion Criteria (Arm 2): 1. Severe motor and /or cognitive disability that would preclude evaluation of progress 2. Limited electrode insertion likely to significantly impact development of speech perception 3. Hearing loss due to bacterial meningitis 4. Dominant language other than English 5. Diagnoses or medical conditions expected to impact language development independent of hearing loss 6. Cochlear nerve deficiency in implanted ears or severe cochlear malformation 7. Children already having spoken language who score better than 25th percentile on the Words and Sentences portion of the CDI language evaluation. 8. Child with more than two months CI experience prior to start of treatment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ann & Robert H. Lurie Children's Hospital of Chicago
RECRUITINGChicago, Illinois, 60611, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A free app might sharpen hearing after cochlear implants — trial puts it to the test
- New hearing aid algorithm aims to cut through noise for clearer speech
- Vision therapy may unlock social skills in children with autism
- Hearing aid microphone showdown: which helps you hear better in noise?
- Brain scans reveal how social training rewires teens with autism and schizophrenia
- New study aims to unlock secrets of hearing in noise for cochlear implant users