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Nerve stretching shows promise for kids with cerebral palsy

NCT ID NCT06485830

Symptom relief Sponsor: University of Seville Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a special nerve-stretching technique (neural mobilization) against standard physical therapy in 40 children aged 5-18 with cerebral palsy and leg spasticity. The goal was to see if it improves joint movement, motor function, and pain. The results may help guide therapy choices for these children.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Sep 2024

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

5 to 17 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Children and adolescents diagnosed with Cerebral Palsy or presence of spasticity and aged between 5 and 18 years. * Level I to IV in the Gross Motor Function Classification System, which denotes that the participant should be able to walk with or without using assistive devices. * Increased muscle tone in the lower extremities, represented by a score greater than 0 on the Tardieu clinical scale and a positive response in the Duncan Ely test. * Ability to communicate pain. * Ability to follow simple commands. Exclusion Criteria: * Have ankle joint arthrodesis or any surgical operation that prevents joint mobilization of the lower limb to some degree. * Any significant change in medication treatment during the study period that may influence (increase or decrease) muscle tone. * Experience uncontrolled epileptic seizures despite medication. * Have received botulinum toxin treatment in the lower limb within the 3 months prior to the study. * Undergo a different physical therapy treatment parallel to that developed in the study.

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Conditions

The condition(s) this trial relates to.

cerebral palsy nervous system disorder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cerebral palsy Neurologic disorder

Contacts and locations

Locations

  • Centro de Atencion Infantil Temprana (CAIT), Universidad de Cordoba

    Córdoba, Cordoba, 14004, Spain

  • University of Sevilla

    Seville, Sevilla, 41009, Spain

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