Experimental therapy uses patients' own cells to deliver chemo directly to tumors
NCT ID NCT07198659
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tests whether a patient's own white blood cells, loaded with a chemotherapy drug, can safely treat unresectable pancreatic cancer. Only 3 people will take part. The main goal is to check for side effects, not to cure the disease.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
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About 3 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18-70 years * Obtain an informed consent form voluntarily signed by the patient themselves * patients with Unresectable Pancreatic Cancer confirmed by Histopathology * Patients who either: 1) have received standard first-line treatments, proven ineffective or causing intolerable adverse effects; or 2) have not received the standard first-line treatments and voluntarily opt for Autologous Drug-Loaded Neutrophils (NeuMed)-based therapy * EOCG score ≤ 2 and expected survival time ≥ 3 months * Liver, kidney and bone marrow functions are basically normal Exclusion Criteria: * Patients who required anti coagulant therapy * Patients with active infectious diseases or a history of bone marrow or organ transplantation * Patients with autoimmune diseases or autoinflammatory diseases * Patients with a history of severe cardiovascular or cerebrovascular diseases or interstitial lung disease or non-infectious pneumonia * Patients who have received live vaccines within 30 days prior to enrollment * Patients with no response to bone marrow mobilization * Other patients deemed unsuitable for enrollment by the investigator
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The First Affiliated Hospital of the PLA Air Force Military Medical University
RECRUITINGXi’an, Shanxi, 710000, China
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Other studies related to the condition(s) this trial covers.
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