A simple nesting technique might soothe newborns during shots
NCT ID NCT07748520
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This trial tests whether a gentle positioning method called nesting—placing a newborn in a snug, flexed posture with rolled towels—can reduce pain and stress during a routine intramuscular injection. About 112 healthy full-term babies born by cesarean section will be randomly assigned to receive nesting or standard care during the injection. Researchers will measure pain, stress, heart rate, breathing, and breastfeeding success to see if this simple, drug-free approach offers comfort.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Nesting (a behavioral positioning intervention using rolled towels or supports to hold the newborn in a flexed, midline posture)
- What this could lead to
- If effective, nesting could offer a simple, drug-free way to reduce pain and stress during routine newborn injections and support breastfeeding success.
- What could go wrong
- This is a small, early-stage trial, and results may not apply broadly. Nesting may not significantly change pain or stress levels, and individual responses can vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 112 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Oct 2025
- Expected to finish
-
Oct 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
Up to 30 minutes
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Written informed consent was obtained from the parent(s) or legal guardian(s) of the newborn. * Born by cesarean section. * Term newborn (gestational age between 37+0 and 41+6 weeks). * Birth weight between 2,500 g and 4,000 g. * Clinically stable vital signs (including heart rate, respiratory rate, and oxygen saturation). * No acute or chronic medical conditions. * No congenital anomalies. * No requirement for endotracheal intubation, resuscitation, or admission to the neonatal intensive care unit (NICU). * Scheduled to receive the first intramuscular injection after birth. Exclusion Criteria: * Multiple birth (e.g., twins or higher-order multiples). * Administration of vitamin K or hepatitis B vaccine before completion of the study procedures. * Withdrawal of parental consent at any time during the study. * Use of a pacifier, oral sucrose, or any pharmacological or non-pharmacological pain-relief intervention before completion of the outcome assessments. * Discharge from the hospital or transfer to another healthcare facility before completion of the study procedures. * Delayed mother-newborn reunion due to maternal general anesthesia or prolonged sedation following spinal or epidural anesthesia. * Delayed transfer of the newborn to the mother because of prolonged surgery, intraoperative complications, or delayed postoperative stabilization.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Breastfeeding success in newborns are added.
Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Kocaeli Darıca Farabi Training and Research Hospital
RECRUITINGDarıca, Kocaeli, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.