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Pain implant repurposed: can zapping nerves wake paralyzed arms?

NCT ID NCT07810712

Symptom relief Sponsor: Walton Centre NHS Foundation Trust Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 09, 2026 · Last updated Sep 10, 2026 · Updated 1 time

Summary

Researchers want to know if a wireless peripheral nerve stimulator, already implanted in some patients for chronic arm pain, can also make paralyzed muscles contract. The trial enrolls adults with stroke or spinal cord injury who have the device on nerves in the arm. Participants undergo nerve and muscle testing, then the device is briefly reprogrammed to trigger a contraction, which is measured and filmed. The goal is to see whether this off-the-shelf system can mimic the grip and release function of older, discontinued implants.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a wireless peripheral nerve stimulator (StimWave/Curonix) reprogrammed to trigger muscle contraction
What this could lead to
If it works, this could offer a simpler, cheaper way to restore grip and release in arms paralyzed by stroke or spinal cord injury, using a device already on the market for pain.
What could go wrong
The trial is very small and tests the device briefly in people who already have an implant for pain, so it cannot show lasting benefit or whether the approach works for everyone with paralysis. Reprogramming carries a risk of discomfort or temporary changes to nerve signaling.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

4 people

The number who actually took part.

Started

Feb 2023

Finished

Aug 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or Female, aged 18 years or above with implanted Curonix (formerly: Stimwave) PNS for radial, ulnar or median nerve; * Functioning lower motor neuron (LMN) pathway determined by baseline EMG. Exclusion Criteria: * Age \<18yr; * Myopathy and other LMN disorders; * Impaired LMN pathway determined by EMG.

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Conditions

The condition(s) this trial relates to.

spinal cord injury stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Paralysis arm Spinal cord injury Stroke

Contacts and locations

Locations

  • The Walton Centre NHS Foundation Trust

    Liverpool, L9 7LJ, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.